USEFULNESS OF A NEW PARAMETER IN FUNCTIONAL ASSESSMENT IN PATIENTS WITH IDIOPATHIC PULMONARY FIBROSIS: DESATURATION- DISTANCE RATIO FROM THE SIX-MINUTE WALK TEST

被引:2
作者
Aktan, Ridvan [1 ,4 ]
Tertemiz, Kemal Can [2 ]
it, Salih Yi [2 ]
Ozalevli, Sevgi [3 ]
Alpaydin, Aylin Ozgen [2 ]
Ucan, Eyup Sabri [2 ]
机构
[1] Izmir Univ Econ, Dept Physiotherapy, Izmir, Turkiye
[2] Dokuz Eylul Univ, Fac Med, Dept Chest Dis, Izmir, Turkiye
[3] Dokuz Eylul Univ, Fac Phys Therapy & Rehabil, Izmir, Turkiye
[4] Izmir Univ Econ, Vocat Sch Hlth Serv, Sakarya St 156, TR-35330 Izmir, Turkiye
关键词
Idiopathic pulmonary fibrosis; Six-minute walk; Exercise; Desaturation; Desaturation distance ratio; EXERCISE CAPACITY; PROGNOSTIC VALUE; STANDARDIZATION;
D O I
10.36141/svdld.v40i2.14634
中图分类号
R56 [呼吸系及胸部疾病];
学科分类号
摘要
Background and aim: New parameters in the 6-minute walk test (6MWT) are needed for assessing exercise capacity in patients with idiopathic pulmonary fibrosis (IPF). To our knowledge, no previous study has investigated the potential of using the desaturation distance ratio (DDR) to assess exercise capacity specifically in patients with IPF. This study aimed to investigate whether DDR is a potential tool for assessing the exercise capacity of patients with IPF. Methods: This study conducted with 33 subjects with IPF. Pulmonary function tests and a 6MWT were performed. To calculate the DDR, first, the difference between the patient's SpO(2) at each minute and the SpO(2) of 100% was summed together to determine the desaturation area (DA). Next, DDR was calculated using dividing DA by the 6-minute walk test distance (6MWD) (i.e., DA/6MWD). Results: When correlations of 6MWD and DDR with changes (.) in the severity of perceived dyspnea were examined, 6MWD did not significantly correlate with Borg. Conversely, there was a significant correlation between the DDR and Borg (r= 0.488, p=0.004). There were significant correlations between 6MWD and FVC % (r=0.370, p=0.034), and FEV1 % (r=0.465, p=0.006). However, DDR was significantly more correlated with FVC % (r= -0.621, p< 0.001), FEV1 % (r= -0.648, p< 0.001). Moreover, there was a significant correlation between DDR and DLCO % (r= -0.342, p=0.052). Conclusions: The findings of this study suggest that DDR is a promising and more useful parameter for assessing patients with IPF.
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共 22 条
[1]  
Amer Thoracic Soc, 2000, AM J RESP CRIT CARE, V161, P646
[2]   Interstitial lung disease: progress and problems [J].
Bourke, S. J. .
POSTGRADUATE MEDICAL JOURNAL, 2006, 82 (970) :494-499
[3]   2-MINUTE, 6-MINUTE, AND 12-MINUTE WALKING TESTS IN RESPIRATORY-DISEASE [J].
BUTLAND, RJA ;
PANG, J ;
GROSS, ER ;
WOODCOCK, AA ;
GEDDES, DM .
BRITISH MEDICAL JOURNAL, 1982, 284 (6329) :1607-1608
[4]  
Chetta A, 2001, SARCOIDOSIS VASC DIF, V18, P170
[5]   ATS statement: Guidelines for the six-minute walk test [J].
Crapo, RO ;
Casaburi, R ;
Coates, AL ;
Enright, PL ;
MacIntyre, NR ;
McKay, RT ;
Johnson, D ;
Wanger, JS ;
Zeballos, RJ ;
Bittner, V ;
Mottram, C .
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2002, 166 (01) :111-117
[6]   Six-minute walk, maximal exercise tests - Reproducibility in fibrotic interstitial pneumonia [J].
Eaton, T ;
Young, P ;
Milne, D ;
Wells, AU .
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2005, 171 (10) :1150-1157
[7]  
Field A., 2013, DISCOVERING STAT USI
[8]   Idiopathic pulmonary fibrosis - Prognostic value of changes in physiology and six-minute-walk test [J].
Flaherty, Kevin R. ;
Andrei, Adin-Cristian ;
Murray, Susan ;
Fraley, Chris ;
Colby, Thomas V. ;
Travis, William D. ;
Lama, Vibha ;
Kazerooni, Ella A. ;
Gross, Barry H. ;
Toews, Galen B. ;
Martinez, Fernando J. .
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2006, 174 (07) :803-809
[9]   Usefulness of the desaturation-distance ratio from the six-minute walk test for patients with COPD [J].
Fujimoto, Yukari ;
Oki, Yutaro ;
Kaneko, Masahiro ;
Sakai, Hideki ;
Misu, Shogo ;
Yamaguchi, Takumi ;
Mitani, Yuji ;
Yasuda, Hisafumi ;
Ishikawa, Akira .
INTERNATIONAL JOURNAL OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE, 2017, 12 :2669-2675
[10]  
GUYATT GH, 1985, CAN MED ASSOC J, V132, P919