Electrochemical Late-Stage Functionalization

被引：131

作者：

Wang, Yulei ^{[1
,2
]}

Dana, Suman ^{[1
,2
]}

Long, Hao ^{[1
,2
]}

Xu, Yang ^{[1
,2
]}

Li, Yanjun ^{[1
,2
]}

Kaplaneris, Nikolaos ^{[1
,2
]}

Ackermann, Lutz ^{[1
,2
]}

机构：

[1] Georg August Univ, Inst Organ & Biomol Chem, D-37077 Gottingen, Germany

[2] Georg August Univ, Wohler Res Inst Sustainable Chem WISCh, D-37077 Gottingen, Germany

来源：

CHEMICAL REVIEWS | 2023年 / 123卷 / 19期

基金：

欧洲研究理事会;

关键词：

C-H FUNCTIONALIZATION; VISIBLE-LIGHT PHOTOCATALYSIS; MEDICINAL CHEMISTS TOOLBOX; CARBON BOND FORMATION; ANODIC-OXIDATION; ELECTROORGANIC CHEMISTRY; N-HYDROXYPHTHALIMIDE; NATURAL-PRODUCTS; ALKYL-HALIDES; ELECTROCATALYTIC APPROACH;

D O I：

10.1021/acs.chemrev.3c00158

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Late-stage functionalization (LSF) constitutes a powerful strategy for the assembly or diversification of novel molecular entities with improved physicochemical or biological activities. LSF can thus greatly accelerate the development of medicinally relevant compounds, crop protecting agents, and functional materials. Electrochemical molecular synthesis has emerged as an environmentally friendly platform for the transformation of organic compounds. Over the past decade, electrochemical late-stage functionalization (eLSF) has gained major momentum, which is summarized herein up to February 2023.

引用

页码：11269 / 11335

页数：67

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