Ventricular arrhythmias, antiarrhythmic therapy and thyroidal illness in advanced heart failure: a case report and review of the literature

被引:0
作者
Alsalama, Fatima [1 ]
Alzaabi, Salma [2 ]
Salloum, Cynthia [3 ]
Younes, Marilyne Abi [4 ]
Bader, Feras [5 ,6 ]
Ghalib, Hussam [5 ]
Atallah, Bassam [2 ,6 ]
机构
[1] United Arab Emirates Univ, Coll Med & Hlth Sci, Al Ain, U Arab Emirates
[2] Cleveland Clin Abu Dhabi, Dept Pharm Serv, POB 112412, Abu Dhabi, U Arab Emirates
[3] Cleveland Clin Abu Dhabi, Med Subspecialties Inst, Dept Endocrinol, Abu Dhabi, U Arab Emirates
[4] Lebanese Amer Univ, Sch Pharm, Byblos, Lebanon
[5] Cleveland Clin Abu Dhabi, Heart & Vasc Inst, POB 112412, Abu Dhabi, U Arab Emirates
[6] Case Western Reserve Univ, Cleveland Clin, Lerner Coll Med, Cleveland, OH 44106 USA
关键词
AMIODARONE-INDUCED THYROTOXICOSIS; SUDDEN CARDIAC DEATH; CONSENSUS DOCUMENT; INTERMACS PROFILES; RHYTHM SOCIETY; ASSOCIATION; MANAGEMENT; HYPERTHYROIDISM; CLASSIFICATION; METAANALYSIS;
D O I
10.1007/s40267-023-00985-3
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
Ventricular arrhythmias are common and can modify the risk profile in patients with advanced heart failure. Guideline-directed medical therapy as well as arrhythmia control are warranted to optimize outcomes and prevent sudden cardiac death. Antiarrhythmic therapy may result in undesired toxicities which can further complicate management. We present a case of an advanced heart failure patient with recurrent ventricular tachycardia and ventricular fibrillation that was refractory to guideline-directed medical therapy and resulted in him being considered for advanced heart failure therapies. We describe the clinical course of antiarrhythmic therapy and the resultant complication of clinically significant thyroid dysfunction. We also summarize our review of the literature regarding the treatment of ventricular arrhythmias in advanced heart failure and the management of antiarrhythmic therapy-induced thyroid dysfunction.
引用
收藏
页码:147 / 155
页数:9
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