Generalized Muscular Hypermetabolism Caused by Mitochondrial Myopathy Shown on 18F-FDG PET/CT

被引:0
作者
Liang, Menglin
Wu, Meiqi
Jia, Chenhao
Guo, Ruijie
Cui, Ruixue
机构
[1] Chinese Acad Med Sci & Peking Union Med Coll, Peking Union Med Coll Hos, Dept Nucl Med, Beijing, Peoples R China
[2] Beijing Key Lab Mol Targeted Diag & Therapy Nucl, Beijing, Peoples R China
关键词
FDG; mitochondrial myopathy; muscle; PET/CT; MUSCLE UPTAKE;
D O I
10.1097/RLU.0000000000004542
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
An 18-year-old man presented with progressive exercise intolerance and muscle weakness for 1 year with recent acute exacerbation. Laboratory test demonstrated lactic acidosis. F-18-FDG PET/CT was performed to exclude malignancy and showed generalized muscular hypermetabolism. Muscle biopsy combined with patient's history suggested mitochondrial myopathy. This report illustrates that mitochondrial myopathy may present as generalized muscular hypermetabolism on F-18-FDG PET/CT and thus should be added to the differential diagnoses.
引用
收藏
页码:359 / 360
页数:2
相关论文
共 8 条
[1]   Diagnosis and Treatment of Mitochondrial Myopathies [J].
Ahmed, Syeda T. ;
Craven, Lyndsey ;
Russell, Oliver M. ;
Turnbull, Doug M. ;
Vincent, Amy E. .
NEUROTHERAPEUTICS, 2018, 15 (04) :943-953
[2]   Detection of multiple muscle involvement in eosinophilic myositis with 18F-FDG PET/CT [J].
Chen, Shu-jun ;
Wang, Xin-yan ;
Hua, Feng-chun ;
Guan, Yi-hui .
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, 2013, 40 (08) :1297-1297
[3]   Diffuse 18F-FDG Muscle Uptake in Trichinella spiralis Infection [J].
Deroose, Christophe M. ;
Van Weehaeghe, Donatienne ;
Tousseyn, Thomas ;
Van Rompuy, Anne-Sophie ;
Vanderschueren, Steven ;
Blockmans, Daniel ;
Gheysens, Olivier .
CLINICAL NUCLEAR MEDICINE, 2016, 41 (01) :55-+
[4]   Mitochondrial diseases [J].
Gorman, Grainne S. ;
Chinnery, Patrick F. ;
DiMauro, Salvatore ;
Hirano, Michio ;
Koga, Yasutoshi ;
McFarland, Robert ;
Suomalainen, Anu ;
Thorburn, David R. ;
Zeviani, Massimo ;
Turnbull, Douglass M. .
NATURE REVIEWS DISEASE PRIMERS, 2016, 2 :1-22
[5]  
Jackson RS, 2006, J NUCL MED TECHNOL, V34, P29
[6]   Diagnosis and treatment of mitochondrial myopathies [J].
Pfeffer, Gerald ;
Chinnery, Patrick F. .
ANNALS OF MEDICINE, 2013, 45 (01) :4-16
[7]  
Soussan M, 2014, CLIN NUCL MED, V39, pE146, DOI 10.1097/RLU.0b013e318279f264
[8]   Clinical values of FDG PET in polymyositis and dermatomyositis syndromes: imaging of skeletal muscle inflammation [J].
Tateyama, Maki ;
Fujihara, Kazuo ;
Misu, Tatsuro ;
Arai, Akira ;
Kaneta, Tomohiro ;
Aoki, Masashi .
BMJ OPEN, 2015, 5 (01)