The first successful case of ABO-incompatible living-donor lobar lung transplantation following desensitization therapy

被引:3
作者
Nakajima, Daisuke [1 ]
Yuasa, Itsuki [1 ]
Kayawake, Hidenao [1 ]
Tanaka, Satona [1 ]
Yamada, Yoshito [1 ]
Yutaka, Yojiro [1 ]
Hamaji, Masatsugu [1 ]
Ohsumi, Akihiro [1 ]
Ikeda, Tadashi [2 ]
Suga, Takenori [3 ]
Baba, Shiro [3 ]
Hiramatsu, Hidefumi [3 ]
Date, Hiroshi [1 ]
机构
[1] Kyoto Univ, Grad Sch Med, Dept Thorac Surg, 54 Shogoin Kawahara Cho,Sakyo Ku, Kyoto 6068507, Japan
[2] Kyoto Univ, Grad Sch Med, Dept Cardiovasc Surg, Kyoto, Japan
[3] Kyoto Univ, Grad Sch Med, Dept Pediat, Kyoto, Japan
关键词
ABO-incompatible; living donor; lung transplantation; desensitization; rituximab; plasmapheresis; ANTIGEN-SPECIFIC IMMUNOADSORPTION; KIDNEY-TRANSPLANTATION; MANAGEMENT; RITUXIMAB;
D O I
10.1016/j.ajt.2023.04.031
中图分类号
R61 [外科手术学];
学科分类号
摘要
ABO-incompatible (ABO-I) living-donor lobar lung transplantation (LDLLT) was successfully performed in a 14-year-old girl who suffered from bronchiolitis obliterans due to graftversus-host disease following hematopoietic stem cell transplantation. In the ABO-I LDLLT procedure, the blood type O patient received a right lower lobe donated from her blood type B father and a left lower lobe donated from her blood type O mother. Desensitization therapy, using rituximab, immunosuppressants, and plasmapheresis, was implemented for 3 weeks prior to transplantation to reduce the production of anti-B antibodies in the recipient and prevent acute antibody-mediated rejection after ABO-I LDLLT.
引用
收藏
页码:1451 / 1454
页数:4
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