Synthesis and Spectral Characteristics of Hydrazinocarbonothioyl Derivatives of Maleopimaric Acid

被引:2
作者
Vafina, G. F. [1 ]
Poptsov, A. I. [1 ]
机构
[1] Russian Acad Sci, Ufa Inst Chem, Ufa Fed Res Ctr, Ufa 450054, Russia
关键词
maleopimaric acid; maleopimarimide; acyl isothiocyanate; hydrazines; spectral characteristics; ANTITUMOR;
D O I
10.1134/S1070363223080042
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Reaction of acyl isothiocyanates of 2-allyl- and 2-benzylmaleopimarimides with 3-carboxy- and 2,4-dinitrophenylhydrazines and hydrazides of some aromatic acids (benzoic, 4-hydroxy- and 4-methoxybenzoic, nicotinic, isonicotinic) furnished linear hydrazinocarbonothioyl derivatives of these maleopimarimides in high yields. Structure of the synthesized compounds was determined by H-1,C-13, H-1-C-13 HSQC, H-1-C-13 HMBC, COSY, NOESY, and H-1-N-15 HMBC NMR spectroscopy methods.
引用
收藏
页码:1955 / 1965
页数:11
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