Aktiia cuffless blood pressure monitor yields equivalent daytime blood pressure measurements compared to a 24-h ambulatory blood pressure monitor: Preliminary results from a prospective single-center study

In this preliminary study, we compared daytime blood pressure (BP) measurements performed by a commercially available cuffless-and continual-BP monitor (Aktiia monitor, Neuchatel, Switzerland) and a traditional ambulatory BP monitor (ABPM; Dyasis 3, Novacor, Paris, France) from 52 patients enrolled in a 12-week cardiac rehabilitation (CR) program (Neuchatel, Switzerland). Daytime (9am-9pm) systolic (SBP) and diastolic (DBP) BP from 7-day averaged data from Aktiia monitor were compared to 1-day averaged BP data from ABPM. No significant differences were found between the Aktiia monitor and the ABPM for SBP (mu +/- sigma [95% confidence interval]: 1.6 +/- 10.5 [-1.5, 4.6] mmHg, P = 0.306; correlation [R-2]: 0.70; +/- 10/ +/- 15 mmHg agreements: 60%, 84%). Marginally non-significant bias was found for DBP (-2.2 +/- 8.0 [-4.5, 0.1] mmHg, P = 0.058; R-2: 0.66; +/- 10/+/- 15 mmHg agreements: 78%, 96%). These intermediate results show that daytime BP measurements using the Aktiia monitor generate data comparable to that of an ABPM monitor.