Is It Safe to Resume Direct Oral Anticoagulants upon Discharge after Hip Fracture Surgery? A Retrospective Study

被引:0
作者
Katzir, Alona [1 ]
Fisher-Negev, Tamar [1 ,2 ]
Or, Omer [1 ]
Jammal, Mahmoud [1 ]
Mosheiff, Ram [1 ]
Weil, Yoram A. [1 ]
机构
[1] Hebrew Univ Jerusalem, Dept Orthoped Surg, Hadassah Med Org, Kalman Yaakov Man St, IL-9112001 Jerusalem, Israel
[2] Hebrew Univ Jerusalem, Inst Drug Res, Sch Pharm, Div Clin Pharm,Fac Med, IL-9190500 Jerusalem, Israel
关键词
reoperation; hip fracture; anticoagulants; LMWH; internal fixation; hemiarthroplasty; PERIOPERATIVE MANAGEMENT; PROPHYLAXIS; ANTIPLATELET; DOACS; NECK;
D O I
10.3390/jcm13010017
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
This study aimed to examine the incidence rate of early reoperations following hip fracture surgery and determine the safety of resuming direct oral anticoagulants. Many orthopedic surgeons are reluctant to resume chronic anticoagulation therapy for patients after surgical intervention for hip fractures. One of the main reasons is the potential for reoperation in the case of surgical complications. We conducted a retrospective cohort study at an Academic Level I trauma center, reviewing the records of 425 geriatric patients (age > 60) who underwent hip fracture surgery between 2018 and 2020, including a subgroup treated with direct oral anticoagulants prior to hospitalization. The study assessed the incidence rate of complications requiring early reoperation. Out of the 425 patients, only nine (2%) required reoperation within a month after discharge, with two (0.5%) on chronic anticoagulation therapy. None of the reoperations were urgent, and all were performed at least 24 h after re-admission. The findings revealed a very low incidence rate of reoperations in patients who underwent hip fracture surgery, with no reoperations performed within 24 h of re-admission. Consequently, we believe that resuming chronic direct oral anticoagulants is a safe and effective approach when discharging patients after hip fracture surgery.
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页数:8
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共 45 条
[1]  
Afshari A, 2018, EUR J ANAESTH, V35, P77, DOI 10.1097/EJA.0000000000000729
[2]   One-Year Mortality Rates Following Fracture of the Femoral Neck Treated With Hip Arthroplasty in an Aging Saudi Population: A Trauma Center Experience [J].
Al-Mohrej, Omar A. ;
Alshaalan, Fawaz N. ;
Aldakhil, Sahar S. ;
Rahman, Wael A. .
GERIATRIC ORTHOPAEDIC SURGERY & REHABILITATION, 2020, 11
[3]   Changes in Anticoagulant Utilization Among United States Nursing Home Residents With Atrial Fibrillation From 2011 to 2016 [J].
Alcusky, Matthew ;
McManus, David D. ;
Hume, Anne L. ;
Fisher, Marc ;
Tjia, Jennifer ;
Lapane, Kate L. .
JOURNAL OF THE AMERICAN HEART ASSOCIATION, 2019, 8 (09)
[4]  
Alpantaki Kalliopi, 2020, Maedica (Bucur), V15, P185, DOI 10.26574/maedica.2020.15.2.185
[5]   Surgeon's experience level and risk of reoperation after hip fracture surgery: an observational study on 30,945 patients in the Norwegian Hip Fracture Register 2011-2015 [J].
Authen, Ane L. ;
Dybvik, Eva ;
Furnes, Ove ;
Gjertsen, Jan-Erik .
ACTA ORTHOPAEDICA, 2018, 89 (05) :496-502
[6]   National Trends in Ambulatory Oral Anticoagulant Use [J].
Barnes, Geoffrey D. ;
Lucas, Eleanor ;
Alexander, G. Caleb ;
Goldberger, Zachary D. .
AMERICAN JOURNAL OF MEDICINE, 2015, 128 (12) :1300-+
[7]   Impact of anticoagulation and antiplatelet drugs on surgery rates and mortality in trauma patients [J].
Blaesius, Felix M. ;
Laubach, Markus ;
Andruszkow, Hagen ;
Luebke, Cavan ;
Lichte, Philipp ;
Lefering, Rolf ;
Hildebrand, Frank ;
Horst, Klemens .
SCIENTIFIC REPORTS, 2021, 11 (01)
[8]   Use of direct oral anticoagulants for postoperative venous thromboembolism prophylaxis after surgery for gynecologic malignancies [J].
Boo, Marilyn ;
Sykes, Peter ;
Simcock, Bryony .
INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER, 2022, 32 (02) :189-194
[9]   Accelerated surgery versus standard care in hip fracture (HIP ATTACK): an international, randomised, controlled trial [J].
Borges, Flavia K. ;
Bhandari, Mohit ;
Guerra-Farfan, Ernesto ;
Patel, Ameen ;
Sigamani, Alben ;
Umer, Masood ;
Tiboni, Maria E. ;
del Mar Villar-Casares, Maria ;
Tandon, Vikas ;
Tomas-Hernandez, Jordi ;
Teixidor-Serra, Jordi ;
Avram, Victoria R. A. ;
Winemaker, Mitchell ;
Ramokgopa, Mmampapatla T. ;
Szczeklik, Wojciech ;
Landoni, Giovanni ;
Wang, Chew Yin ;
Begum, Dilshad ;
Neary, John D. ;
Adili, Anthony ;
Sancheti, Parag K. ;
Lawendy, Abdel-Rahman ;
Balaguer-Castro, Mariano ;
Sleczka, Pawel ;
Jenkinson, Richard J. ;
Nur, Aamer Nabi ;
Wood, Gavin C. A. ;
Feibel, Robert J. ;
McMahon, Stephen J. ;
Sigamani, Alen ;
Popova, Ekaterine ;
Biccard, Bruce M. ;
Moppett, Iain K. ;
Forget, Patrice ;
Landais, Paul ;
McGillion, Michael H. ;
Vincent, Jessica ;
Balasubramanian, Kumar ;
Harvey, Valerie ;
Garcia-Sanchez, Yaiza ;
Pettit, Shirley M. ;
Gauthier, Leslie P. ;
Guyatt, Gordon H. ;
Conen, David ;
Garg, Amit X. ;
Bangdiwala, Shrikant I. ;
Belley-Cote, Emilie P. ;
Marcucci, Maura ;
Lamy, Andre ;
Whitlock, Richard .
LANCET, 2020, 395 (10225) :698-708
[10]  
Colwell CW, 2005, ORTHOPEDICS, V28, P143