Two new quinolinone glycoalkaloids from Chrysanthemum indicum L. and their antimicrobial activity

被引：3

作者：

Zhu, Qingsong ^{[1
]}

Liu, Songhu ^{[1
]}

Zhai, Min ^{[1
]}

Qiao, Xinrong ^{[1
]}

Chen, Qiong ^{[1
]}

Zhu, Nailiang ^{[1
]}

机构：

[1] Xinyang Agr & Forestry Univ, Xinyang, Henan, Peoples R China

来源：

NATURAL PRODUCT RESEARCH | 2025年 / 39卷 / 02期

关键词：

Chrysanthemum indicum L; compositae; quinolinone glycoalkaloids; antimicrobial activity; ALKALOIDS; CONSTITUENTS; EXTRACTS;

D O I：

10.1080/14786419.2023.2262719

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

Phytochemical investigation of Chrysanthemum indicum L. yielded two new quinolinone glycoalkaloids named as Chrysanthemumsides A-B (1-2). The structures of the new compounds were elucidated by analysis of their 1D- and 2D-NMR, HRESIMS and ECD calculations. Compounds 1-4 were evaluated for antimicrobial activity against the Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa and Candida albicans, and the data showed that compound 2 had significant antimicrobial effects (MIC 3.9 to 7.8 mu g/mL).

引用

页码：279 / 286

页数：8

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