Transmission dynamics of a novel HIV/AIDS model through a higher-order Galerkin time discretization scheme

被引:4
作者
Attaullah [1 ]
Zeb, Kamil [1 ]
Khan, Ilyas [2 ]
Ahmad, Riaz M. [3 ]
Eldin, Sayed [4 ]
机构
[1] Bacha Khan Univ, Dept Math & Stat, Charsadda 24461, Pakistan
[2] Majmaah Univ, Coll Sci Al Zulfi, Dept Math, Al Majmaah 11952, Saudi Arabia
[3] Nanjing Univ Informat Sci & Technol, Dept Math & Stat, Nanjing, Peoples R China
[4] Future Univ Egypt, Fac Engn, Ctr Res, New Cairo 11835, Egypt
关键词
HIV-INFECTION; ANTIRETROVIRAL THERAPY; NUMERICAL-SOLUTION; CHEMOTHERAPY;
D O I
10.1038/s41598-023-34696-6
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
There are numerous contagious diseases caused by pathogenic microorganisms, including bacteria, viruses, fungi, and parasites, that have the propensity to culminate in fatal consequences. A communicable disease is an illness caused by a contagion agent or its toxins and spread directly or indirectly to a susceptible animal or human host by an infected person, animal, vector, or immaterial environment. Human immunodeficiency virus (HIV) infection, hepatitis A, B, and C, and measles are all examples of communicable diseases. Acquired immunodeficiency syndrome (AIDS) is a communicable disease caused by HIV infection that has become the most severe issue facing humanity. The research work in this paper is to numerically explore a mathematical model and demonstrate the dynamics of HIV/AIDS disease transmission using a continuous Galerkin-Petrov time discretization of a higher-order scheme, specifically the cGP(2)-scheme. Depict a graphical and tabular comparison between the outcomes of the mentioned scheme and those obtained through other classical schemes that exist in the literature. Further, a comparison is performed relative to the well-known fourth-order Ruge-Kutta (RK4) method with different step sizes. By contrast, the suggested approach provided more accurate results with a larger step size than RK4 with a smaller step size. After validation and confirmation of the suggested scheme and code, we implement the method to the extended model by introducing a treatment rate and show the impact of various non-linear source terms for the generation of new cells. We also determined the basic reproduction number and use the Routh-Hurwitz criterion to assess the stability of disease-free and unique endemic equilibrium states of the HIV model.
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页数:20
相关论文
共 40 条
[1]  
Ammassari A, 2001, J ACQ IMMUN DEF SYND, V28, P445, DOI 10.1097/00042560-200112150-00006
[2]  
[Anonymous], 2015, MATH MOD HIV AIDS RE
[3]   Mathematical Analysis and Numerical Solution of a Model of HIV with a Discrete Time Delay [J].
Arenas, Abraham J. ;
Gonzalez-Parra, Gilberto ;
Naranjo, Jhon J. ;
Cogollo, Myladis ;
De La Espriella, Nicolas .
MATHEMATICS, 2021, 9 (03) :1-21
[4]   On the comparative performance of fourth order Runge-Kutta and the Galerkin-Petrov time discretization methods for solving nonlinear ordinary differential equations with application to some mathematical models in epidemiology [J].
Attaullah ;
Yassen, Mansour F. ;
Alyobi, Sultan ;
Al-Duais, Fuad S. ;
Weera, Wajaree .
AIMS MATHEMATICS, 2022, 8 (02) :3699-3729
[5]   A study on the transmission and dynamical behavior of an HIV/AIDS epidemic model with a cure rate [J].
Attaullah ;
Alyobi, Sultan ;
Yassen, Mansour F. .
AIMS MATHEMATICS, 2022, 7 (09) :17507-17528
[6]   Galerkin time discretization scheme for the transmission dynamics of HIV infection with non-linear supply rate [J].
Attaullah ;
Drissi, Ramzi ;
Weera, Wajaree .
AIMS MATHEMATICS, 2022, 7 (06) :11292-11310
[7]   Mathematical modeling and numerical simulation of HIV infection model [J].
Attaullah ;
Sohaib, Muhammad .
RESULTS IN APPLIED MATHEMATICS, 2020, 7
[8]  
Attaullah K.Z., INFLUENCE SATURATED
[9]   A higher order Galerkin time discretization scheme for the novel mathematical model of COVID-19 [J].
Attaullah, Muhammad ;
Jawad, Muhammad ;
Alyobi, Sultan ;
Yassen, Mansour F. ;
Weera, Wajaree .
AIMS MATHEMATICS, 2023, 8 (02) :3763-3790
[10]  
Butcher J.C., 2008, Numerical Methods for Ordinary Differential Equations, DOI DOI 10.1002/9781119121534.CH4