A non-invasive optical method for anaemia detection

被引:1
作者
Chamola, Paritosh [1 ]
Mittal, Poornima [1 ]
机构
[1] Delhi Technol Univ, Dept Elect & Commun Engn, Delhi 110042, India
关键词
organic solar cell; biomedical; anaemia; haemoglobin; photovoltaic; ELECTRONIC SPECTRAL PROPERTIES; ZINC PHTHALOCYANINE; FLUORESCENT DYES; BLOOD; COUMARIN; TISSUE; COLOR; CELL; EFFICIENT; CARRIER;
D O I
10.1088/1402-4896/acd5b8
中图分类号
O4 [物理学];
学科分类号
0702 ;
摘要
The latest non-invasive biomedical electronic sensors are capable of providing continuous reliable information, for instance oxygenation level of blood, level of glucose etc. These biomedical sensors are in general based on the electro-chemical or spectral properties of the substances. The absorption of blood in infrared and visible range is prominently determined by haemoglobin. The coefficient of absorption for blood is different at different wavelengths. This optical absorption characteristic of the blood yields the vital information on the composition of the blood. Haemoglobin is primarily used to measure the status of anaemia, in developing countries like India and other African countries numerous people with greater health needs don't have access to proper diagnostic facilities. Therefore, an introduction of portable, low cost and non-invasive Haemoglobin detector will give a vast opportunity for screening the population suffering with anaemia. The present article purposes a non-invasive method of haemoglobin detection comprising of an organic photovoltaic cell and three LED's sources i.e., blue, green and red which are used with their respective radiation spectral range of 450-495 nm, 495-570 nm and 620-750 nm to illuminate an area of the skin on finger, this transmitted light after interacting with tissues is detected by an arrangement of Coumarin 30 : C-60/NN '-QA/ZnPc active layer based organic solar cell. Thus, the approach provide in this article presents a simple, biocompatible and flexible means for assessing blood haemoglobin level by utilizing an multi spectral optical processing method. The method developed herein could further be integrated to wearable electronic devices.
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页数:11
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共 52 条
  • [31] Nielsen K.P., 2008, P S SOLAR RAD HUMAN, P35
  • [32] Diffusing-wave spectroscopy with dynamic contrast variation: disentangling the effects of blood flow and extravascular tissue shearing on signals from deep tissue
    Ninck, Markus
    Untenberger, Markus
    Gisler, Thomas
    [J]. BIOMEDICAL OPTICS EXPRESS, 2010, 1 (05): : 1502 - 1513
  • [33] Preparation of a water-soluble fluorinated zinc phthalocyanine and its effect for photodynamic therapy
    Oda, K
    Ogura, S
    Okura, I
    [J]. JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY, 2000, 59 (1-3) : 20 - 25
  • [34] Light scattering of human red blood cells during metabolic remodeling of the membrane
    Park, YongKeun
    Best-Popescu, Catherine A.
    Dasari, Ramachandra R.
    Popescu, Gabriel
    [J]. JOURNAL OF BIOMEDICAL OPTICS, 2011, 16 (01)
  • [35] Static and dynamic light scattering of healthy and malaria-parasite invaded red blood cells
    Park, YongKeun
    Diez-Silva, Monica
    Fu, Dan
    Popescu, Gabriel
    Choi, Wonshik
    Barman, Ishan
    Suresh, Subra
    Feld, Michael S.
    [J]. JOURNAL OF BIOMEDICAL OPTICS, 2010, 15 (02)
  • [36] Metabolic remodeling of the human red blood cell membrane
    Park, YongKeun
    Best, Catherine A.
    Auth, Thorsten
    Gov, Nir S.
    Safran, Samuel A.
    Popescu, Gabriel
    Suresh, Subra
    Feld, Michael S.
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2010, 107 (04) : 1289 - 1294
  • [37] Capillary versus venous haemoglobin determination in the assessment of healthy blood donors
    Patel, A. J.
    Wesley, R.
    Leitman, S. F.
    Bryant, B. J.
    [J]. VOX SANGUINIS, 2013, 104 (04) : 317 - 323
  • [38] Efficient, high-bandwidth organic multilayer photodetectors
    Peumans, P
    Bulovic, V
    Forrest, SR
    [J]. APPLIED PHYSICS LETTERS, 2000, 76 (26) : 3855 - 3857
  • [39] Prahl S., 1998, Tabulated Molar Extinction Coefficient for Hemoglobin in Water
  • [40] Roberts V. C., 1982, Transactions of the Institute of Measurement and Control, V4, P101, DOI 10.1177/014233128200400205