Meningitis patients with pneumonia: correlation between blood parameters and clinical features

被引:1
|
作者
Lu, Liuyi [1 ]
Li, Taijie [3 ]
Chen, Huaping [1 ]
Zhang, Linyan [1 ]
Chen, Mingxing [1 ]
Peng, Qiliu [2 ]
Qin, Xue [1 ]
机构
[1] Guangxi Med Univ, Dept Clin Lab, Affiliated Hosp 1, Nanning 530021, Guangxi, Peoples R China
[2] Guangxi Int Zhuang Med Hosp, Dept Clin Lab, Nanning 530201, Guangxi, Peoples R China
[3] Guangxi Med Univ, Dept Lab Med, Wuming Hosp, Nanning 530199, Guangxi, Peoples R China
关键词
CRP; D-dimer; ESR; meningitis; meningitis complications; pneumonia infection; CELL DISTRIBUTION WIDTH; PROGNOSTIC-SIGNIFICANCE; CANCER; INFLAMMATION; CARCINOMA; ASSOCIATION; MORTALITY; TELOMERE; RISK;
D O I
10.2217/bmm-2022-0565
中图分类号
R-3 [医学研究方法]; R3 [基础医学];
学科分类号
1001 ;
摘要
Plain language summaryD-dimer has an early and rapid diagnostic value for the hypercoagulation state. C-reactive protein (CRP) and erythrocyte sedimentation rate (ESR) have been widely used laboratory parameters for inflammatory diseases. In our study, we observed increased D-dimer, CRP and ESR levels in patients with meningitis, which were more pronounced in patients with meningitis complicated with pneumonia. It is worth noting that D-dimer and CRP showed a positive correlation in patients with meningitis. D-dimer, CRP and ESR in patients with meningitis can effectively monitor disease progression. Background: This research aimed to explore the possible relationship between the main experimental parameters and clinical status in meningitis patients with pneumonia infection. Methods: A retrospective analysis of the demographic characteristics, clinical features and laboratory parameters of meningitis patients was performed. Results: D-dimer, C-reactive protein (CRP) and erythrocyte sedimentation rate (ESR) exhibited good diagnostic ability for meningitis complicated with pneumonia. Additionally, we observed a positive correlation between D-dimer and CRP in cases of meningitis with pneumonia infection. D-dimer, ESR and Streptococcus pneumoniae (S. pneumoniae) were independently associated with meningitis patients with pneumonia infection. Conclusion: D-dimer, CRP, ESR and S. pneumoniae infection may effectively anticipate disease progression and adverse consequences in meningitis patients with pneumonia infection.
引用
收藏
页码:1269 / 1278
页数:10
相关论文
共 50 条
  • [41] Correlation between Blood and CSF Compartment Cytokines and Chemokines in Subjects with Cryptococcal Meningitis
    Okafor, Elizabeth C.
    Hullsiek, Katherine H.
    Williams, Darlisha A.
    Scriven, James E.
    Rhein, Joshua
    Nabeta, Henry W.
    Musubire, Abdu K.
    Rajasingham, Radha
    Muzoora, Conrad
    Schutz, Charlotte
    Meintjes, Graeme
    Meya, David B.
    Boulware, David R.
    MEDIATORS OF INFLAMMATION, 2020, 2020
  • [42] Investigation of correlation between PET/CT findings and clinical parameters in Patients with multiple myeloma
    Wang, Rongfu
    Di, Lijuan
    Zhang, Jianhua
    Zhao, Guangyu
    Fan, Yan
    Fu, Zhanli
    Zhang, Xuchu
    Jiang, Qiao
    JOURNAL OF NUCLEAR MEDICINE, 2017, 58
  • [43] Clinical features and prognostic factors in elderly patients with aspiration pneumonia
    Kim, Seo Woo
    Ryu, Yon Ju
    Lee, Seok Jung
    Lee, Jin Hwa
    Chang, Jung Hyun
    Shim, Sung Shine
    EUROPEAN RESPIRATORY JOURNAL, 2012, 40
  • [44] Clinical features of COVID-19 pneumonia in elderly patients
    Debiche, Soumaya
    Sahnoun, Imen
    Ben Saad, Soumaya
    Dabbebi, Fatma Ezzahra
    Ben Mansour, Ameni
    Zaafouri, Asma
    Ben Sassi, Sarra
    Daghfous, Hafaoua
    Maalej, Sonia
    Tritar, Fatma
    El Gharbi, Leila Douik
    Debiche, Soumaya
    EUROPEAN RESPIRATORY JOURNAL, 2021, 58
  • [45] Evaluation of epidemiological and clinical features of patients with pneumococcal and legionella pneumonia
    Rabooki, Tina
    Hashemi, Seyed Hamid
    Rabooki, Diana
    Ghasemibasir, Hamidreza
    Karami, Manochehr
    BIOMEDICAL AND BIOTECHNOLOGY RESEARCH JOURNAL, 2019, 3 (03): : 176 - 181
  • [46] ACUTE NONLYMPHOBLASTIC LEUKEMIA - CORRELATION BETWEEN CLINICAL AND HEMATOLOGICAL PARAMETERS IN 87 ADULT PATIENTS
    PERSEGHIN, P
    INVERNIZZI, R
    GIRINO, M
    FORTUNATO, A
    CASALONE, R
    ASCARI, E
    HAEMATOLOGICA, 1987, 72 (05) : 425 - 430
  • [47] Diffuse mesothelioma of the peritoneum: correlation between histological and clinical parameters and survival in 73 patients
    Liu, Sandy
    Staats, Paul
    Lee, Michael
    Alexander, H. Richard
    Burke, Allen P.
    PATHOLOGY, 2014, 46 (07) : 604 - 609
  • [48] Investigation of correlation between PET/CT findings and clinical parameters in patients with multiple myeloma
    Wang, R.
    Di, L.
    Zhang, J.
    Zhao, G.
    Fan, Y.
    Fu, Z.
    Zhang, X.
    Jiang, Q.
    EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, 2017, 44 : S730 - S730
  • [49] Correlation between Baseline PET/CT Findings and Clinical Parameters in Multiple Myeloma Patients
    Arcay, A.
    Aydin, F.
    Caglayan, C. N. Dundar
    Vural, E.
    Iltar, U.
    Engin, M. N.
    Kiprak, Z. G.
    Boz, A.
    EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, 2021, 48 (SUPPL 1) : S358 - S358
  • [50] Infectious pneumonia in immunocompetent patients: updates in clinical and imaging features
    Lee, Kyung Soo
    Kim, Tae Jung
    Peck, Kyong Ran
    Han, Joungho
    PRECISION AND FUTURE MEDICINE, 2018, 2 (03): : 79 - 94