Acute myocardial infarction after inactivated COVID-19 vaccination: a case report and literature review

被引：7

作者：

Ou, Weimei ^{[1
]}

Wang, Bin ^{[1
]}

Zhang, Guoming ^{[1
]}

Ding, Licheng ^{[1
]}

Liu, Zhixian ^{[1
]}

Wu, Kaimin ^{[1
]}

Sun, Guangfeng ^{[1
]}

Huang, Chengmin ^{[1
]}

Li, Zhaokai ^{[1
]}

Feng, Shuyuan ^{[1
]}

Gao, Rui ^{[2
]}

机构：

[1] Xiamen Univ, Xiamen Cardiovasc Hosp, Sch Med, Dept Emergency, Xiamen, Peoples R China

[2] Xiamen Univ, Xiamen Cardiovasc Hosp, Inst Cardiovasc Dis, Sch Med, Xiamen, Peoples R China

来源：

FRONTIERS IN CARDIOVASCULAR MEDICINE | 2023年 / 10卷

关键词：

acute myocardial infarction (AMI); COVID-19; vaccination; kounis syndrome (KS); coronary heart disease (CHD); coronary thrombosis; KOUNIS-SYNDROME; VACCINES;

D O I：

10.3389/fcvm.2023.1123385

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

A number of vaccines have been developed and deployed globally to restrain the spreading of the coronavirus disease 2019 (COVID-19). The adverse effect following vaccination is an important consideration. Acute myocardial infarction (AMI) is a kind of rare adverse event after COVID-19 vaccination. Herein, we present a case of an 83-year-old male who suffered cold sweat ten minutes after the first inactivated COVID-19 vaccination and AMI one day later. The emergency coronary angiography showed coronary thrombosis and underlying stenosis in his coronary artery. Type II Kounis syndrome might be a potential mechanism, which is manifested as coronary thrombosis secondary to allergic reactions in patients with underlying asymptomatic coronary heart disease. We also summarize the reported AMI cases post COVID-19 vaccination, as well as overview and discuss the proposed mechanisms of AMI after COVID-19 vaccination, thus providing insights for clinicians to be aware of the possibility of AMI following COVID-19 vaccination and potential underlying mechanisms.

引用

页数：7

共 39 条

[1] Safety of COVID-19 vaccines [J].

Aga, Qutaiba A. Al Khames ;

Alkhaffaf, Waseem H. ;

Hatem, Tagreed H. ;

Nassir, Kawthar F. ;

Batineh, Yazan ;

Dahham, Abdullah T. ;

Shaban, Dimah ;

Aga, Luma A. Al Khames ;

Agha, Manhal Y. R. ;

Traqchi, Muaamar .

JOURNAL OF MEDICAL VIROLOGY, 2021, 93 (12) :6588-6594

[2] Kounis syndrome must be considered in the differential diagnosis of myocardial infarction following COVID-19 vaccination [J].

Allam, C. ;

Saouma, M. ;

Chlawit, Roy .

QJM-AN INTERNATIONAL JOURNAL OF MEDICINE, 2022, 115 (11) :783-784

[3] Acute myocardial infarction and myocarditis following COVID-19 vaccination [J].

Aye, Y. N. ;

Mai, A. S. ;

Zhang, A. ;

Lim, O. Z. H. ;

Lin, N. ;

Ng, C. H. ;

Chan, M. Y. ;

Yip, J. ;

Loh, P-H ;

Chew, N. W. S. .

QJM-AN INTERNATIONAL JOURNAL OF MEDICINE, 2023, 116 (04) :279-283

[4] Efficacy and Safety of the mRNA-1273 SARS-CoV-2 Vaccine [J].

Baden, Lindsey R. ;

El Sahly, Hana M. ;

Essink, Brandon ;

Kotloff, Karen ;

Frey, Sharon ;

Novak, Rick ;

Diemert, David ;

Spector, Stephen A. ;

Rouphael, Nadine ;

Creech, C. Buddy ;

McGettigan, John ;

Khetan, Shishir ;

Segall, Nathan ;

Solis, Joel ;

Brosz, Adam ;

Fierro, Carlos ;

Schwartz, Howard ;

Neuzil, Kathleen ;

Corey, Larry ;

Gilbert, Peter ;

Janes, Holly ;

Follmann, Dean ;

Marovich, Mary ;

Mascola, John ;

Polakowski, Laura ;

Ledgerwood, Julie ;

Graham, Barney S. ;

Bennett, Hamilton ;

Pajon, Rolando ;

Knightly, Conor ;

Leav, Brett ;

Deng, Weiping ;

Zhou, Honghong ;

Han, Shu ;

Ivarsson, Melanie ;

Miller, Jacqueline ;

Zaks, Tal .

NEW ENGLAND JOURNAL OF MEDICINE, 2021, 384 (05) :403-416

[5] Myocardial infarction following COVID-19 vaccine administration; a systematic review [J].

Baqi, Dana H. ;

Kakamad, Fahmi H. ;

Mahmood, Zana H. ;

Fattah, Fattah H. ;

Ahmed, Shaho F. ;

Hassan, Marwan N. ;

Amin, Bnar J. Hama ;

Mohammed, Shvan H. ;

Mikael, Tomas M. ;

Hassan, Hunar A. ;

Salh, Abdulwahid M. .

HELIYON, 2022, 8 (11)

[6] Safety of the BNT162b2 mRNA Covid-19 Vaccine in a Nationwide Setting [J].

Barda, Noam ;

Dagan, Noa ;

Ben-Shlomo, Yatir ;

Kepten, Eldad ;

Waxman, Jacob ;

Ohana, Reut ;

Hernan, Miguel A. ;

Lipsitch, Marc ;

Kohane, Isaac ;

Netzer, Doron ;

Reis, Ben Y. ;

Balicer, Ran D. .

NEW ENGLAND JOURNAL OF MEDICINE, 2021, 385 (12) :1078-1090

[7] Myocardial Infarction Following COVID-19 Vaccine Administration: Post Hoc, Ergo Propter Hoc? [J].

Baronti, Arianna ;

Gentile, Francesco ;

Manetti, Alice Chiara ;

Scatena, Andrea ;

Pellegrini, Silvia ;

Pucci, Angela ;

Franzini, Maria ;

Castiglione, Vincenzo ;

Maiese, Aniello ;

Giannoni, Alberto ;

Pistello, Mauro ;

Emdin, Michele ;

Aquaro, Giovanni Donato ;

Di Paolo, Marco .

VIRUSES-BASEL, 2022, 14 (08)

[8] Analysis of COVID-19 Vaccine Type and Adverse Effects Following Vaccination [J].

Beatty, Alexis L. ;

Peyser, Noah D. ;

Butcher, Xochitl E. ;

Cocohoba, Jennifer M. ;

Lin, Feng ;

Olgin, Jeffrey E. ;

Pletcher, Mark J. ;

Marcus, Gregory M. .

JAMA NETWORK OPEN, 2021, 4 (12)

[9] Vaccine allergies [J].

Chung, Eun Hee .

CLINICAL AND EXPERIMENTAL VACCINE RESEARCH, 2014, 3 (01) :50-57

[10] Anaphylaxis mediated myocardial infarction in a coronary graft: A new variant of Kounis syndrome (a case report) [J].

Dazy, Kristen ;

Walters, Daniel ;

Holland, Christine ;

Baldwin, James .

INTERNATIONAL JOURNAL OF CARDIOLOGY, 2013, 168 (02) :E84-E85

← 1 2 3 4 →