Reagentless protein-based electrochemical biosensors

被引：6
|
作者：
Silva, Saimon M. M. [1 ,3 ,4 ,5 ]
Li, Miaosi [1 ]
Mendes, Alexandre Xavier [2 ,3 ]
Moulton, Simon E. E. [2 ,3 ,4 ]
机构：
[1] Universal Biosensors, Rowville, Vic 3178, Australia
[2] Swinburne Univ Technol, ARC Ctr Excellence Electromat Sci, Sch Sci Comp & Engn Technol, Melbourne, Vic 3122, Australia
[3] St Vincents Hosp Melbourne, Aikenhead Ctr Med Discovery, Melbourne, Vic 3065, Australia
[4] Swinburne Univ Technol, Iverson Hlth Innovat Res Inst, Melbourne, Vic 3122, Australia
[5] La Trobe Univ, La Trobe Inst Mol Sci, Dept Chem & Phys, Melbourne, Vic 3086, Australia
来源：
ANALYST | 2023年 / 148卷 / 09期
关键词：
FLUORESCENCE POLARIZATION; LUBRICIN; STRATEGIES; ASSAY;
D O I：
10.1039/d3an00341h
中图分类号：
O65 [分析化学];
学科分类号：
070302 ; 081704 ;
摘要：
The creation of reagentless protein-based biosensors that are capable of monitoring molecular analytes directly in bodily fluids could revolutionize our understanding of biology and personalized health monitoring. The limited number of molecular sensors that are currently available in the market depends on the specific enzymatic or chemical reactivity of their target analytes and therefore are not applicable to many relevant biomarkers. Aiming to overcome this limited molecular sensing generality, a new class of reagentless protein-based electrochemical sensors has been introduced for the direct measurements of biomarkers in unprocessed biological fluids. This mini-review will discuss the most recent cutting-edge discoveries for the development of electroanalytical modular biosensors, where all the sensors' components are integrated into a self-sufficient sensor allowing hence its autonomous functionality.
引用
收藏
页码：1930 / 1938
页数：9
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