Reagentless protein-based electrochemical biosensors

被引：6
|
作者：
Silva, Saimon M. M. [1 ,3 ,4 ,5 ]
Li, Miaosi [1 ]
Mendes, Alexandre Xavier [2 ,3 ]
Moulton, Simon E. E. [2 ,3 ,4 ]
机构：
[1] Universal Biosensors, Rowville, Vic 3178, Australia
[2] Swinburne Univ Technol, ARC Ctr Excellence Electromat Sci, Sch Sci Comp & Engn Technol, Melbourne, Vic 3122, Australia
[3] St Vincents Hosp Melbourne, Aikenhead Ctr Med Discovery, Melbourne, Vic 3065, Australia
[4] Swinburne Univ Technol, Iverson Hlth Innovat Res Inst, Melbourne, Vic 3122, Australia
[5] La Trobe Univ, La Trobe Inst Mol Sci, Dept Chem & Phys, Melbourne, Vic 3086, Australia
来源：
ANALYST | 2023年 / 148卷 / 09期
关键词：
FLUORESCENCE POLARIZATION; LUBRICIN; STRATEGIES; ASSAY;
D O I：
10.1039/d3an00341h
中图分类号：
O65 [分析化学];
学科分类号：
070302 ; 081704 ;
摘要：
The creation of reagentless protein-based biosensors that are capable of monitoring molecular analytes directly in bodily fluids could revolutionize our understanding of biology and personalized health monitoring. The limited number of molecular sensors that are currently available in the market depends on the specific enzymatic or chemical reactivity of their target analytes and therefore are not applicable to many relevant biomarkers. Aiming to overcome this limited molecular sensing generality, a new class of reagentless protein-based electrochemical sensors has been introduced for the direct measurements of biomarkers in unprocessed biological fluids. This mini-review will discuss the most recent cutting-edge discoveries for the development of electroanalytical modular biosensors, where all the sensors' components are integrated into a self-sufficient sensor allowing hence its autonomous functionality.
引用
收藏
页码：1930 / 1938
页数：9
相关论文
共 50 条
  • [11] Glucose biosensors as models for the development of advanced protein-based biosensors
    Staiano, M
    Bazzicalupo, P
    Rossi, M
    D'Auria, S
    MOLECULAR BIOSYSTEMS, 2005, 1 (5-6) : 354 - 362
  • [12] A reagentless electrochemical biosensor based on a protein scaffold
    Jhaveri, SD
    Mauro, JM
    Goldston, HM
    Schauer, CL
    Tender, LM
    Trammell, SA
    CHEMICAL COMMUNICATIONS, 2003, (03) : 338 - 339
  • [13] Non-antibody protein-based biosensors
    Ferrigno, Paul Ko
    BIOSENSOR TECHNOLOGIES FOR DETECTION OF BIOMOLECULES, 2016, 60 (01): : 19 - 25
  • [14] Sensing second messengersFluorescent protein-based biosensors
    Katharine H. Wrighton
    Nature Cell Biology, 2009, 11 (Suppl 1) : S20 - S21
  • [15] In Situ Construction of Protein-Based Semisynthetic Biosensors
    Ueda, Tsuyoshi
    Tamura, Tomonori
    Hamachi, Itaru
    ACS SENSORS, 2018, 3 (03): : 527 - 539
  • [16] Maximizing the performance of protein-based fluorescent biosensors
    Chai, Fu
    Cheng, Dazhou
    Nasu, Yusuke
    Terai, Takuya
    Campbell, Robert E.
    BIOCHEMICAL SOCIETY TRANSACTIONS, 2023, 51 (04) : 1585 - 1595
  • [17] Fluorescent Protein-Based Biosensors and Their Clinical Applications
    Ohba, Yusuke
    Fujioka, Yoichiro
    Nakada, Shigeyuki
    Tsuda, Masumi
    FLUORESCENCE-BASED BIOSENSORS: FROM CONCEPTS TO APPLICATIONS, 2013, 113 : 313 - 348
  • [18] Designs and applications of fluorescent protein-based biosensors
    Ibraheem, Andreas
    Campbell, Robert E.
    CURRENT OPINION IN CHEMICAL BIOLOGY, 2010, 14 (01) : 30 - 36
  • [19] S-layer protein-based biosensors
    Schuster, B.
    NEW BIOTECHNOLOGY, 2018, 44 : S21 - S21
  • [20] Protein-based voltammetric biosensors fabricated with nanomaterials
    Zhang, Dongmei
    Zhao, Jing
    Li, Genxi
    PROTEIN AND PEPTIDE LETTERS, 2008, 15 (08): : 764 - 771
12345