Impact of age for overall survival in head and neck sarcoma

被引：1

作者：

Suzuki, Hidenori ^{[1
,8
]}

Takano, Gaku ^{[2
]}

Tsukushi, Satoshi ^{[3
]}

Ando, Masashi ^{[4
]}

Yatabe, Yasushi ^{[5
]}

Kodaira, Takeshi ^{[6
]}

Nishikawa, Daisuke ^{[1
]}

Beppu, Shintaro ^{[1
]}

Hasegawa, Yasuhisa ^{[7
]}

Hanai, Nobuhiro ^{[1
]}

机构：

[1] Aichi Canc Ctr Hosp, Dept Head & Neck Surg, Nagoya, Japan

[2] Nagoya City Univ, Dept Otolaryngol Head & Neck Surg, Grad Sch Med Sci, Nagoya, Japan

[3] Aichi Canc Ctr Hosp, Dept Orthoped Surg, Nagoya, Japan

[4] Aichi Canc Ctr Hosp, Dept Clin Oncol, Nagoya, Japan

[5] Aichi Canc Ctr Hosp, Dept Pathol & Mol Diagnost, Nagoya, Japan

[6] Aichi Canc Ctr Hosp, Dept Radiat Oncol, Nagoya, Japan

[7] Asahi Univ, Dept Head & Neck Surg, Gifu, Japan

[8] Aichi Canc Ctr Hosp, Dept Head & Neck Surg, 1-1 Kanokoden,Chikusa-ku, Nagoya 4648681, Japan

来源：

MEDICINE | 2023年 / 102卷 / 07期

关键词：

age; chemotherapy; head and neck sarcoma; overall survival; predictor; CURRENT UPDATE; OSTEOSARCOMA; CHEMOTHERAPY; MANAGEMENT; DIAGNOSIS;

D O I：

10.1097/MD.0000000000032966

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The purpose to the present study is to research the association between age at surgery and survival outcomes of patients with sarcoma in head and neck. Twenty-six patients with head and neck sarcoma who underwent by surgery from 2003 to 2017 were enrolled in the present observation study. Patients who did not undergo chemotherapy were significantly older age at surgery by Mann-Whitney U test. Fifty-five was the cutoff age that predicted death by receiver operating curve analysis. Shorter survival rates of overall, disease-specific, local recurrence-free and disease-free were associated with older age by log-rank test. Age (>= 55 years/<55 years) was correlated with shorter overall survival by multivariate analysis of Cox's proportional hazards model adjusting with chemotherapy (absence/presence). In conclusion, older age predicts worse overall survival in head and neck sarcoma.

引用

页数：5

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