Mutant-specific pharmacological inhibition of KRAS in multiple myeloma and functional genomics studies to identify mechanisms regulating myeloma cell response vs. resistance to KRAS inhibition

被引:0
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作者
Steinbrunn, Torsten [1 ,2 ,3 ,4 ]
Shirasaki, Ryosuke [1 ,2 ,3 ,5 ,6 ]
Dashevsky, Olga [1 ,2 ,3 ]
Tang, Huihui [1 ,2 ,3 ,5 ]
Yamano, Shizuka [1 ,2 ]
Teoh, Phaik Ju [1 ,2 ,3 ,7 ,8 ]
Leypoldt, Lisa [1 ,2 ,3 ,9 ]
Sugihara, Takeru [1 ,2 ,3 ]
Mizuno, Rin [1 ,2 ,3 ]
Kaji, Mariko [1 ]
Sorrell, Jeffrey [1 ,2 ]
Glassner, Brian [1 ,2 ,3 ]
Simoes, Ricardo de Matos [1 ,2 ,3 ]
Christensen, James [10 ]
Mitsiades, Constantine [1 ,2 ,3 ,5 ]
机构
[1] Dana Farber Canc Inst, Dept Med Oncol, Boston, MA 02115 USA
[2] Harvard Med Sch, Dept Med, Boston, MA 02115 USA
[3] Massachusetts Inst Technol MIT & Harvard, Broad Inst, Cambridge, MA USA
[4] Univ Hosp Wurzburg, Dept Med 2, Wurzburg, Germany
[5] Harvard Med Sch, Ludwig Ctr, Boston, MA 02115 USA
[6] Teikyo Univ Med, Dept Hematol Oncol, Tokyo, Japan
[7] Natl Univ Singapore, Yong Loo Lin Sch Med, Dept Med, Singapore, Singapore
[8] Natl Univ Singapore, Canc Sci Inst Singapore, Singapore, Singapore
[9] Univ Med Ctr Hamburg Eppendorf, Dept Hematol Oncol & Bone Marrow Transplantat, Sect Pneumol, Hamburg, Germany
[10] Mirati Therapeut Inc, San Diego, CA USA
来源
CLINICAL LYMPHOMA MYELOMA & LEUKEMIA | 2023年 / 23卷
关键词
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中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
P-371
引用
收藏
页码:S244 / S244
页数:1
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