Interleukin-6 Receptor Polymorphism Attenuates Clonal Hematopoiesis-Mediated Coronary Artery Disease Risk Among 451 180 Individuals in the UK Biobank

被引:46
作者
Vlasschaert, Caitlyn [1 ]
Heimlich, J. Brett [3 ]
Rauh, Michael J. [2 ]
Natarajan, Pradeep [5 ,6 ,7 ,8 ]
Bick, Alexander G. [4 ]
机构
[1] Queens Univ, Dept Med, Kingston, ON, Canada
[2] Queens Univ, Dept Pathol & Mol Med, Kingston, ON, Canada
[3] Vanderbilt Univ, Div Cardiol, Med Ctr, Nashville, TN 37232 USA
[4] Vanderbilt Univ, Med Ctr, Div Med Genet, Dept Med, Nashville, TN 37232 USA
[5] Massachusetts Gen Hosp, Cardiovasc Res Ctr, Boston, MA 02114 USA
[6] Massachusetts Gen Hosp, Ctr Genom Med, Boston, MA 02114 USA
[7] Broad Inst MIT & Harvard, Program Med & Populat Genet & Cardiovasc Dis, Cambridge, MA 02142 USA
[8] Harvard Med Sch, Dept Med, Boston, MA 02115 USA
关键词
clonal hematopoiesis; coronary artery disease; inflammation; interleukin;
D O I
10.1161/CIRCULATIONAHA.122.062126
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
引用
收藏
页码:358 / 360
页数:3
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Vlasschaert C, 2022, medRxiv, DOI [10.1101/2022.10.21.22281368, 10.1101/2022.10.21.22281368, DOI 10.1101/2022.10.21.22281368]