Prefrontal and somatosensory-motor cortex effective connectivity in humans

被引：37

作者：

Rolls, Edmund T. ^{[1
,2
,3
]}

Deco, Gustavo ^{[4
,5
,6
]}

Huang, Chu-Chung ^{[7
,8
]}

Feng, Jianfeng ^{[2
,3
]}

机构：

[1] Oxford Ctr Computat Neurosci, Oxford, England

[2] Univ Warwick, Dept Comp Sci, Coventry CV4 7AL, W Midlands, England

[3] Fudan Univ, Inst Sci & Technol Brain Inspired Intelligence, Shanghai 200403, Peoples R China

[4] Univ Pompeu Fabra, Ctr Brain & Cognit, Dept Informat & Commun Technol, Computat Neurosci Grp, Roc Boronat 138, Barcelona 08018, Spain

[5] Pompeu Fabra Univ, Brain & Cognit, Barcelona 08018, Spain

[6] Univ Pompeu Fabra, Inst Catalana Recerca & Estudis Avancats ICREA, Passeig Luis Companys 23, Barcelona 08010, Spain

[7] East China Normal Univ, Sch Psychol & Cognit Sci, Inst Brain & Educ Innovat, Shanghai Key Lab Brain Funct Genom,Minist Educ, Shanghai 200602, Peoples R China

[8] Shanghai Ctr Brain Sci & Brain Inspired Technol, Shanghai 200602, Peoples R China

来源：

CEREBRAL CORTEX | 2023年 / 33卷 / 08期

基金：

欧盟地平线“2020”; 国家重点研发计划;

关键词：

prefrontal cortex; insula; somatosensory cortex; effective connectivity; human connectome; CAUDOLATERAL ORBITOFRONTAL CORTEX; COMPARATIVE CYTOARCHITECTONIC ANALYSIS; PRIMATE TASTE CORTEX; GUSTATORY RESPONSES; SINGLE NEURONS; MACAQUE MONKEY; FUNCTIONAL ARCHITECTURE; VISUAL SPACE; REWARD VALUE; FAT TEXTURE;

D O I：

10.1093/cercor/bhac391

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Effective connectivity, functional connectivity, and tractography were measured between 57 cortical frontal and somatosensory regions and the 360 cortical regions in the Human Connectome Project (HCP) multimodal parcellation atlas for 171 HCP participants. A ventral somatosensory stream connects from 3b and 3a via 1 and 2 and then via opercular and frontal opercular regions to the insula, which then connects to inferior parietal PF regions. This stream is implicated in "what"-related somatosensory processing of objects and of the body and in combining with visual inputs in PF. A dorsal "action" somatosensory stream connects from 3b and 3a via 1 and 2 to parietal area 5 and then 7. Inferior prefrontal regions have connectivity with the inferior temporal visual cortex and orbitofrontal cortex, are implicated in working memory for "what" processing streams, and provide connectivity to language systems, including 44, 45, 47l, TPOJ1, and superior temporal visual area. The dorsolateral prefrontal cortex regions that include area 46 have connectivity with parietal area 7 and somatosensory inferior parietal regions and are implicated in working memory for actions and planning. The dorsal prefrontal regions, including 8Ad and 8Av, have connectivity with visual regions of the inferior parietal cortex, including PGs and PGi, and are implicated in visual and auditory top-down attention.

引用

页码：4939 / 4963

页数：25

共 157 条

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