The Role of the Gut Microbiota in Anorexia Nervosa in Children and Adults-Systematic Review

被引：2

作者：

Anton-Paduraru, Dana-Teodora ^{[1
,2
]}

Trofin, Felicia ^{[3
,4
]}

Nastase, Eduard Vasile ^{[4
,5
]}

Miftode, Radu Stefan ^{[6
,7
]}

Miftode, Ionela-Larisa ^{[4
,5
]}

Trandafirescu, Mioara Florentina ^{[8
]}

Cojocaru, Elena ^{[2
,9
]}

Tarca, Elena ^{[2
,10
]}

Mindru, Dana Elena ^{[1
,2
]}

Dorneanu, Olivia Simona ^{[3
,4
]}

机构：

[1] Grigore T Popa Univ Med & Pharm, Dept Mother & Child Med Genet, Iasi 700115, Romania

[2] Sf Maria Children Emergency Hosp, Iasi 700309, Romania

[3] Grigore T Popa Univ Med & Pharm, Dept Prevent Med & Interdisciplinar Microbiol, Iasi 700115, Romania

[4] Clin Hosp Infect Dis Sf Parascheva, Iasi 700116, Romania

[5] Grigore T Popa Univ Med & Pharm, Dept Internal Med Infect Dis 2, Iasi 700115, Romania

[6] Grigore T Popa Univ Med & Pharm, Dept Internal Med Cardiol 1, Iasi 700115, Romania

[7] Sf Spiridon Clin Hosp, Iasi 700111, Romania

[8] Grigore T Popa Univ Med & Pharm, Dept Morphofunct Sci Histol 1, Iasi 700115, Romania

[9] Grigore T Popa Univ Med & Pharm, Dept Morphofunct Sci Pathol 1, Iasi 700115, Romania

[10] Grigore T Popa Univ Med & Pharm, Dept Surg Pediat Surg 2, Iasi 700115, Romania

来源：

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES | 2024年 / 25卷 / 01期

关键词：

microbiota; gut-brain axis; anorexia; children; adults; INTESTINAL MICROBIOTA; EATING-DISORDERS; NUTRIENT INTAKE; ANXIETY; BRAIN; STRESS; DEPRESSION; PREVALENCE; BEHAVIOR;

D O I：

10.3390/ijms25010041

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Among the factors incriminated in the appearance of eating disorders, intestinal microbiota has recently been implicated. Now there is evidence that the composition of gut microbiota is different in anorexia nervosa. We gathered many surveys on the changes in the profile of gut microbiota in patients with anorexia nervosa. This review comprehensively examines the contemporary experimental evidence concerning the bidirectional communication between gut microbiota and the brain. Drawing from recent breakthroughs in this area of research, we propose that the gut microbiota significantly contributes to the intricate interplay between the body and the brain, thereby contributing to overall healthy homeostasis while concurrently impacting disease risk, including anxiety and mood disorders. Particular attention is devoted to elucidating the structure and functional relevance of the gut microbiota in the context of Anorexia Nervosa.

引用

页数：22

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