Cardiovascular dysautonomia in postacute sequelae of SARS-CoV-2 infection

被引:3
作者
Stahlberg, Marcus [1 ,2 ]
Mahdi, Ali [1 ,2 ]
Johansson, Madeleine [3 ,4 ]
Fedorowski, Artur [1 ,2 ,3 ]
Olshansky, Brian [5 ]
机构
[1] Karolinska Inst, Dept Med Solna, Cardiol Unit, Stockholm, Sweden
[2] Karolinska Univ Hosp, Dept Cardiol, Stockholm, Sweden
[3] Lund Univ, Dept Clin Sci, Malmo, Sweden
[4] Skane Univ Hosp, Dept Cardiol, Malmo, Sweden
[5] Univ Iowa Hosp, 200 Hawkins Dr, Iowa City, IA 52242 USA
关键词
autonomic nervous system; COVID-19; postacute COVID-29 syndrome; postural orthostatic tachycardia syndrome; INAPPROPRIATE SINUS TACHYCARDIA; ORTHOSTATIC TACHYCARDIA; DYSFUNCTION; SYMPTOMS; COVID-19; PATHOPHYSIOLOGY; INFLAMMATION; PERSISTENCE; ACTIVATION; MANAGEMENT;
D O I
10.1111/jce.16117
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Coronavirus disease 2019 (COVID-19) has led to a worldwide pandemic that continues to transform but will not go away. Cardiovascular dysautonomia in postacute sequelae of severe acute respiratory syndrome coronavirus 2 infection has led to persistent symptoms in a large number of patients. Here, we define the condition and its associated symptoms as well as potential mechanisms responsible. We provide a careful and complete overview of the topic addressing novel studies and a generalized approach to the management of individuals with this complex and potentially debilitating problem. We also discuss future research directions and the important knowledge gaps to be addressed in ongoing and planned studies.
引用
收藏
页码:608 / 617
页数:10
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