Risk Factors Associated with Loss to Follow-up Among Transgender Women Receiving HIV Pre-exposure Prophylaxis in Chiang Mai province, Thailand

被引：3

作者：

Thongsak, Natthapat ^{[1
]}

Manojai, Natthaporn ^{[2
]}

Apiputhipan, Rathawit ^{[2
]}

Rongram, Nicha ^{[3
]}

Mattawanon, Natnita ^{[4
]}

Bunyatisai, Walaithip ^{[1
,5
]}

Plubin, Bandhita ^{[1
,5
]}

Nakharutai, Nawapon ^{[1
,5
]}

Thumronglaohapun, Salinee ^{[1
,5
]}

Srikummoon, Pimwarat ^{[1
,5
]}

Wongsawat, Kanokkan ^{[1
]}

Traisathit, Patrinee ^{[1
,5
,6
]}

Homkham, Nontiya ^{[7
]}

机构：

[1] Chiang Mai Univ, Fac Sci, Dept Stat, Chiang Mai, Thailand

[2] Mplus Fdn, Chiang Mai, Thailand

[3] FHI360, Bangkok, Thailand

[4] Chiang Mai Univ, Fac Med, Dept Obstet & Gynecol, Chiang Mai, Thailand

[5] Chiang Mai Univ, Fac Sci, Data Sci Res Ctr, Dept Stat, Chiang Mai, Thailand

[6] Chiang Mai Univ, Res Ctr Bioresources Agr Ind & Med, Chiang Mai, Thailand

[7] Thammasat Univ, Fac Publ Hlth, Pathum Thani, Thailand

来源：

AIDS AND BEHAVIOR | 2023年 / 27卷 / 02期

关键词：

Transgender women; PrEP; Loss to follow-up; Preventing HIV; Thailand; SEX; PREVENTION; MEN; PERCEPTION; IMPACT; MSM;

D O I：

10.1007/s10461-022-03782-7

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

Although HIV pre-exposure prophylaxis (PrEP) is free in Thailand, many transgender women discontinue taking it after initiation. We determined the loss to follow-up (LTFU) rate of transgender women who initiated PrEP at the Mplus Foundation, Chiang Mai, Thailand, and identified associated risk factors using Cox proportional hazard models. Of 235 participants who initiated PrEP, 59 (55%) out of 108 remaining participants had reactive syphilis. The LTFU rate at 6 months was 38% (95% confidence interval [CI]: 29-48%). Multivariable analysis indicates that LTFU is independently associated with age >= 26 years old (adjusted hazard ratio [aHR] = 2.09; 95% CI: 1.06-4.14) and reactive syphilis (aHR = 1.98; 95% CI:1.01-3.88). Delayed appointment scheduling by the PrEP providers and the syphilis clinic was associated with transgender women having reactive syphilis, and the lockdown policy during the COVID-19 pandemic might have influenced them to discontinue PrEP and their subsequent LTFU.

引用

页码：473 / 483

页数：11

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