The 2022 outbreak and the pathobiology of the coxsackie virus [hand foot and mouth disease] in India

被引:11
作者
Chavan, Nutan A. [1 ]
Lavania, Mallika [1 ]
Shinde, Pooja [1 ]
Sahay, Rima [2 ]
Joshi, Madhuri [1 ]
Yadav, Pragya D. [2 ]
Tikute, Sanjaykumar [1 ]
Waghchaure, Rishabh [1 ]
Ashok, M. [3 ]
Gupta, Anjli [4 ]
Mittal, Mahima [5 ]
Khan, Vikram [6 ]
Fomda, Bashir A. [7 ]
Ahmad, Muneer [7 ]
Tiwari, Ved Pratap [8 ]
Pote, Pralhad [9 ]
Dhongade, Ashish Ramchandra [10 ]
Mohanty, Aroop [5 ]
Mohan, Kriti [5 ]
Kumar, Manish [5 ]
Bhardwaj, Anchala [5 ]
机构
[1] Natl Inst Virol, Enter Viruses Grp, ICMR, Pune, Maharashtra, India
[2] Natl Inst Virol, Maximum Containment Lab, ICMR, Pune, Maharashtra, India
[3] NIV, Bangalore Unit, Bangalore, Karnataka, India
[4] SP Med Coll Bikaner, Dept Microbiol, Bikaner, Rajasthan, India
[5] AIIMS Gorakhpur, Dept Pediat, Gorakhpur, Uttar Pradesh, India
[6] UT Dadar Nagar Haveli & Daman & Diu, Integrated Dis Surveillance Programme IDSP, Silvassa, India
[7] Sherikashmir Inst Med Sci, Dept Microbiol, Srinagar, J&K, India
[8] Smt Kashibai Navale Med Coll, Dept Pathol, Pune, Maharashtra, India
[9] Noble Hosp, Pune, Maharashtra, India
[10] Shaishav Hosp, Pune, Maharashtra, India
关键词
HFMD; Tomato flu; Enterovirus; Coxsackievirus A-16; Coxsackievirus A-6; India; ONYCHOMADESIS; SPAIN;
D O I
10.1016/j.meegid.2023.105432
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
Outbreaks of HFMD in children aged <5 years have been reported worldwide and the major causative agents are Coxsackievirus (CV) A16, enterovirus (EV)-A71 and recently CVA6. In India, HFMD is a disease that is not commonly reported. The purpose of the study was to identify the enterovirus type(s) associated with large outbreak of Hand, foot, and mouth disease during COVID-19 pandemic in 2022. Four hundred and twenty five clinical samples from 196-suspected cases were collected from different parts of the country. This finding indicated the emergence of CVA6 in HFMD along with CVA16, soon after the gradual easing of non-pharmaceutical interventions during-pandemic COVID-19 and the relevance of continued surveillance of circulating enterovirus types in the post-COVID pandemic era.
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