The association between internal polycyclic aromatic hydrocarbons exposure and risk of Obesity-A systematic review with meta-analysis

被引：15
作者：
Liu, Chunyu [1 ]
Liu, Qisijing [3 ]
Song, Shanjun [1 ,2 ,5 ]
Li, Weixia [1 ]
Feng, Yuanyuan [1 ]
Cong, Xiangru [1 ]
Ji, Yaqin [4 ]
Li, Penghui [1 ,2 ]
机构：
[1] Tianjin Univ Technol, Sch Environm Sci & Safety Engn, Tianjin 300384, Peoples R China
[2] Tianjin Key Lab Hazardous Waste Safety Disposal &, Tianjin 300384, Peoples R China
[3] Nankai Univ, Res Inst Publ Hlth, Tianjin 300071, Peoples R China
[4] Nankai Univ, Coll Environm Sci & Engn, Tianjin 300071, Peoples R China
[5] Natl Inst Metrol, Beijing 100029, Peoples R China
来源：
CHEMOSPHERE | 2023年 / 329卷
基金：
中国博士后科学基金;
关键词：
Polycyclic aromatic hydrocarbons; Obesity; Meta-analysis; Systematic review; URINARY BIOMARKERS; INDOOR AIR; HEALTH; CHILDREN; ENVIRONMENTS; IMPACT; DIET;
D O I：
10.1016/j.chemosphere.2023.138669
中图分类号：
X [环境科学、安全科学];
学科分类号：
08 ; 0830 ;
摘要：
Exposure to polycyclic aromatic hydrocarbons (PAHs) is emerging as a risk factor for obesity, but with conflicting findings. The aim of this systematic review is to investigate and summarize the current evidence towards the associations between PAHs exposure and risk of obesity. We conducted a systematic search of online databases, including PubMed, Embase, Cochrane Library, and Web of Science up to April 28, 2022. Eight cross-sectional studies with data from 68,454 participants were included. The present study illustrated that there was a sig-nificant positive association between naphthalene (NAP), phenanthrene (PHEN), and total OH-PAH metabolites and risk of obesity, the pooled OR (95% CI) was estimated at 1.43 (1.07, 1.90), 1.54 (1.18, 2.02), and 2.29 (1.32, 3.99), respectively. However, there was no significant association between fluorene (FLUO) and1-hydroxypyrene (1-OHP) metabolite and risk of obesity. Subgroup analyses showed that associations between PAHs exposure and risk of obesity were more apparent in children, female, smokers and developing regions.
引用
收藏
页数：11
相关论文
共 62 条
[1]   Fgr kinase is required for proinflammatory macrophage activation during diet-induced obesity [J].
Acin-Perez, Rebeca ;
Iborra, Salvador ;
Marti-Mateos, Yolanda ;
Cook, Emma C. L. ;
Conde-Garrosa, Ruth ;
Petcherski, Anton ;
del Mar Munoz, Ma ;
Martinez de Mena, Raquel ;
Krishnan, Karthickeyan Chella ;
Jimenez, Concepcion ;
Pedro Bolanos, Juan ;
Laakso, Markku ;
Lusis, Aldon J. ;
Shirihai, Orian S. ;
Sancho, David ;
Antonio Enriquez, Jose .
NATURE METABOLISM, 2020, 2 (09) :974-+
[2]   Health Effects of Overweight and Obesity in 195 Countries over 25 Years [J].
Afshin, Ashkan ;
Forouzanfar, Mohammad H. ;
Reitsma, Marissa B. ;
Sur, Patrick ;
Estep, Kara ;
Lee, Alex ;
Marczak, Laurie ;
Mokdad, Ali H. ;
Moradi-Lakeh, Maziar ;
Naghavi, Mohsen ;
Salama, Joseph S. ;
Vos, Theo ;
Abate, Kalkidan H. ;
Abbafati, Cristiana ;
Ahmed, Muktar B. ;
Al-Aly, Ziyad ;
Alkerwi, Ala'a ;
Al-Raddadi, Rajaa ;
Amare, Azmeraw T. ;
Amberbir, Alemayehu ;
Amegah, Adeladza K. ;
Amini, Erfan ;
Amrock, Stephen M. ;
Anjana, Ranjit M. ;
Arnlov, Johan ;
Asayesh, Hamid ;
Banerjee, Amitava ;
Barac, Aleksandra ;
Baye, Estifanos ;
Bennett, Derrick A. ;
Beyene, Addisu S. ;
Biadgilign, Sibhatu ;
Biryukov, Stan ;
Bjertness, Espen ;
Boneya, Dube J. ;
Campos-Nonato, Ismael ;
Carrero, Juan J. ;
Cecilio, Pedro ;
Cercy, Kelly ;
Ciobanu, Liliana G. ;
Cornaby, Leslie ;
Damtew, Solomon A. ;
Dandona, Lalit ;
Dandona, Rakhi ;
Dharmaratne, Samath D. ;
Duncan, Bruce B. ;
Eshrati, Babak ;
Esteghamati, Alireza ;
Feigin, Valery L. ;
Fernandes, Joao C. .
NEW ENGLAND JOURNAL OF MEDICINE, 2017, 377 (01) :13-27
[3]   Polycyclic aromatic hydrocarbons in milk and dairy products [J].
Amirdivani, Shabboo ;
Khorshidian, Nasim ;
Dana, Maryam Ghobadi ;
Mohammadi, Reza ;
Mortazavian, Amir M. ;
Quiterio de Souza, Simone Lorena ;
Rocha, Henrique Barbosa ;
Raices, Renata .
INTERNATIONAL JOURNAL OF DAIRY TECHNOLOGY, 2019, 72 (01) :120-131
[4]  
Bergman A, 2013, State of the Science of Endocrine Disrupting Chemicals 2012
[5]   Polycyclic aromatic hydrocarbons and female reproductive health: A scoping review [J].
Bolden, Ashley L. ;
Rochester, Johanna R. ;
Schultz, Kim ;
Kwiatkowski, Carol F. .
REPRODUCTIVE TOXICOLOGY, 2017, 73 :61-74
[6]   Association of urinary polycyclic aromatic hydrocarbons and obesity in children aged 3-18: Canadian Health Measures Survey 2009-2015 [J].
Bushnik, Tracey ;
Wong, Suzy L. ;
Holloway, Alison C. ;
Thomson, Errol M. .
JOURNAL OF DEVELOPMENTAL ORIGINS OF HEALTH AND DISEASE, 2020, 11 (06) :623-631
[7]   Psychological and behavioral effects of genetic risk testing for obesity: a systematic review [J].
Cheera, Emily K. ;
Klarich, DawnKylee S. ;
Hong, Mee Young .
PERSONALIZED MEDICINE, 2016, 13 (03) :265-277
[8]   Diet derived polycyclic aromatic hydrocarbons and its pathogenic roles in colorectal carcinogenesis [J].
Cheng, Tracie ;
Lam, Alfred K. ;
Gopalan, Vinod .
CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY, 2021, 168
[9]   Urinary biomarkers of polycyclic aromatic hydrocarbons in pre- and peri-pubertal girls in Northern California: Predictors of exposure and temporal variability [J].
Dobraca, Dina ;
Lum, Raymond ;
Sjodin, Andreas ;
Calafat, Antonia M. ;
Laurent, Cecile A. ;
Kushi, Lawrence H. ;
Windham, Gayle C. .
ENVIRONMENTAL RESEARCH, 2018, 165 :46-54
[10]   Human dietary exposure to polycyclic aromatic hydrocarbons: A review of the scientific literature [J].
Domingo, Jose L. ;
Nadal, Marti .
FOOD AND CHEMICAL TOXICOLOGY, 2015, 86 :144-153
1234567