Recombinant production of antimicrobial peptides in plants

被引:12
作者
Nazarian-Firouzabadi, Farhad [1 ,7 ]
Torres, Marcelo Der Torossian [2 ,3 ,4 ,5 ,6 ]
de la Fuente-Nunez, Cesar [3 ,5 ,7 ]
机构
[1] Lorestan Univ, Fac Agr, Prod Engn & Plant Genet Dept, POB 465, Khorramabad, Iran
[2] Univ Penn, Inst Biomed Informat, Inst Translat Med & Therapeut, Perelman Sch Med,Dept Psychiat,Machine Biol Grp, Philadelphia, PA USA
[3] Univ Penn, Inst Biomed Informat, Inst Translat Med & Therapeut, Perelman Sch Med,Dept Microbiol,Machine Biol Grp, Philadelphia, PA USA
[4] Univ Penn, Sch Engn & Appl Sci, Dept Bioengn, Philadelphia, PA USA
[5] Univ Penn, Sch Engn & Appl Sci, Dept Chem & Biomol Engn, Philadelphia, PA USA
[6] Univ Penn, Penn Inst Computat Sci, Philadelphia, PA USA
[7] Univ Penn, Perelman Sch Med, Sch Engn & Appl Sci, Machine Biol Grp, Philadelphia, PA 19104 USA
基金
美国国家卫生研究院;
关键词
Antimicrobial peptides; Recombinant technology; Genetic engineering; Transgenic plants; PATHOGEN-INDUCED EXPRESSION; ANTIFUNGAL PEPTIDES; ENHANCED RESISTANCE; DISEASE RESISTANCE; ESCHERICHIA-COLI; DEFENSE PEPTIDES; CATIONIC PEPTIDE; RATIONAL DESIGN; PROTEIN; BACTERIAL;
D O I
10.1016/j.biotechadv.2023.108296
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
Classical plant breeding methods are limited in their ability to confer disease resistance on plants. However, in recent years, advancements in molecular breeding and biotechnological have provided new approaches to overcome these limitations and protect plants from disease. Antimicrobial peptides (AMPs) constitute promising agents that may be able to protect against infectious agents. Recently, peptides have been recombinantly produced in plants at scale and low cost. Because AMPs are less likely than conventional antimicrobials to elicit resistance of pathogenic bacteria, they open up exciting new avenues for agricultural applications. Here, we review recent advances in the design and production of bioactive recombinant AMPs that can effectively protect crop plants from diseases.
引用
收藏
页数:12
相关论文
共 180 条
[1]  
Abiri R, 2016, CURR ISSUES MOL BIOL, V18, P21
[2]   Lactoferrin a multiple bioactive protein: An overview [J].
Abril Garcia-Montoya, Isui ;
Siqueiros Cendon, Tania ;
Arevalo-Gallegos, Sigifredo ;
Rascon-Cruz, Quintin .
BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS, 2012, 1820 (03) :226-236
[3]   Biologically Active Peptides from Venoms: Applications in Antibiotic Resistance, Cancer, and Beyond [J].
Ageitos, Lucia ;
Torres, Marcelo D. T. ;
de la Fuente-nunez, Cesar .
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2022, 23 (23)
[4]  
Akishiba M, 2017, NAT CHEM, V9, P751, DOI [10.1038/NCHEM.2779, 10.1038/nchem.2779]
[5]   Plants rendered herbicide-susceptible by cauliflower mosaic virus-elicited suppression of a 35S promoter-regulated transgene [J].
Al-Kaff, NS ;
Kreike, MM ;
Covey, SN ;
Pitcher, R ;
Page, AM ;
Dale, PJ .
NATURE BIOTECHNOLOGY, 2000, 18 (09) :995-999
[6]  
Alibakhshi A., 2018, Scientific Journal of Agriculture, V41, P87
[7]   Characterization of two novel defense peptides from pea (Pisum sativum) seeds [J].
Almeida, MS ;
Cabral, KMS ;
Zingali, RB ;
Kurtenbach, E .
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 2000, 378 (02) :278-286
[8]   Improving the Activity of Trp-Rich Antimicrobial Peptides by Arg/Lys Substitutions and Changing the Length of Cationic Residues [J].
Arias, Mauricio ;
Piga, Kathlyn B. ;
Hyndman, M. Eric ;
Vogel, Hans J. .
BIOMOLECULES, 2018, 8 (02)
[9]   Fusion of a chitin-binding domain to an antibacterial peptide to enhance resistance to Fusarium solani in tobacco (Nicotiana tabacum) [J].
Badrhadad, Azam ;
Nazarian-Firouzabadi, Farhad ;
Ismaili, Ahmad .
3 BIOTECH, 2018, 8 (09)
[10]   Antimicrobial Peptides [J].
Bahar, Ali Adem ;
Ren, Dacheng .
PHARMACEUTICALS, 2013, 6 (12) :1543-1575