Complement inhibitors for the treatment of geographic atrophy

被引:10
作者
Chew, Emily Y. [1 ]
机构
[1] NEI, Div Epidemiol & Clin Applicat, NIH, Bethesda, MD 20892 USA
关键词
MACULAR DEGENERATION;
D O I
10.1016/S0140-6736(23)01844-5
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
引用
收藏
页码:1396 / 1398
页数:3
相关论文
共 8 条
[1]  
Apellis, 2023, Apellis provides update on review of rare safety events with SYFOVRE (pegcetacoplan injection) for geographic atrophy.
[2]   Pegcetacoplan for the treatment of geographic atrophy secondary to age-related macular degeneration (OAKS and DERBY): two multicentre, randomised, double-masked, sham-controlled, phase 3 trials [J].
Heier, Jeffrey S. ;
Lad, Eleonora M. ;
Holz, Frank G. ;
Rosenfeld, Philip J. ;
Guymer, Robyn H. ;
Boyer, David ;
Grossi, Federico ;
Baumal, Caroline R. ;
Korobelnik, Jean-Francois ;
Slakter, Jason S. ;
Waheed, Nadia K. ;
Metlapally, Ravi ;
Pearce, Ian ;
Steinle, Nathan ;
Francone, Anibal A. ;
Hu, Allen ;
Lally, David R. ;
Deschatelets, Pascal ;
Francois, Cedric ;
Bliss, Caleb ;
Staurenghi, Giovanni ;
Mones, Jordi ;
Singh, Rishi P. ;
Ribeiro, Ramiro ;
Wykoff, Charles C. .
LANCET, 2023, 402 (10411) :1434-1448
[3]   C5 Inhibitor Avacincaptad Pegol for Geographic Atrophy Due to Age-Related Macular Degeneration A Randomized Pivotal Phase 2/3 Trial [J].
Jaffe, Glenn J. ;
Westby, Keith ;
Csaky, Karl G. ;
Mones, Jordi ;
Pearlman, Joel A. ;
Patel, Sunil S. ;
Joondeph, Brian C. ;
Randolph, John ;
Masonson, Harvey ;
Rezaei, Kourous A. .
OPHTHALMOLOGY, 2021, 128 (04) :576-586
[4]   Efficacy and safety of avacincaptad pegol in patients with geographic atrophy (GATHER2): 12-month results from a randomised, double-masked, phase 3 trial [J].
Khanani, Arshad M. ;
Patel, Sunil S. ;
Staurenghi, Giovanni ;
Tadayoni, Ramin ;
Danzig, Carl J. ;
Eichenbaum, David A. ;
Hsu, Jason ;
Wykoff, Charles C. ;
Heier, Jeffrey S. ;
Lally, David R. ;
Mones, Jordi ;
Nielsen, Jared S. ;
Sheth, Veeral S. ;
Kaiser, Peter K. ;
Clark, Julie ;
Zhu, Liansheng ;
Patel, Hersh ;
Tang, Justin ;
Desai, Dhaval ;
Jaffe, Glenn J. .
LANCET, 2023, 402 (10411) :1449-1458
[5]   Complement C3 Inhibitor Pegcetacoplan for Geographic Atrophy Secondary to Age-Related Macular Degeneration A Randomized Phase 2 Trial [J].
Liao, David S. ;
Grossi, Federico, V ;
El Mehdi, Delphine ;
Gerber, Monica R. ;
Brown, David M. ;
Heier, Jeffrey S. ;
Wykoff, Charles C. ;
Singerman, Lawrence J. ;
Abraham, Prema ;
Grassmann, Felix ;
Nuernberg, Peter ;
Weber, Bernhard H. F. ;
Deschatelets, Pascal ;
Kim, Robert Y. ;
Chung, Carol Y. ;
Ribeiro, Ramiro M. ;
Hamdani, Mohamed ;
Rosenfeld, Philip J. ;
Boyer, David S. ;
Slakter, Jason S. ;
Francois, Cedric G. .
OPHTHALMOLOGY, 2020, 127 (02) :186-195
[6]   Avacincaptad pegol for geographic atrophy secondary to age-related macular degeneration: 18-month findings from the GATHER1 trial [J].
Patel, Sunil S. ;
Lally, David R. ;
Hsu, Jason ;
Wykoff, Charles C. ;
Eichenbaum, David ;
Heier, Jeffrey S. ;
Jaffe, Glenn J. ;
Westby, Keith ;
Desai, Dhaval ;
Zhu, Liansheng ;
Khanani, Arshad M. .
EYE, 2023, 37 (17) :3551-3557
[7]   C3 Function and Inhibition in Geographic Atrophy: Interesting Insights from a Phase 2 Study [J].
Wong, Wai T. .
OPHTHALMOLOGY, 2020, 127 (02) :196-197
[8]   Global prevalence of age-related macular degeneration and disease burden projection for 2020 and 2040: a systematic review and meta-analysis [J].
Wong, Wan Ling ;
Su, Xinyi ;
Li, Xiang ;
Cheung, Chui Ming G. ;
Klein, Ronald ;
Cheng, Ching-Yu ;
Wong, Tien Yin .
LANCET GLOBAL HEALTH, 2014, 2 (02) :E106-E116