Obesity in COVID-19 patients is a complex interaction

Objective: To assess role of obesity in Covid-19 patients on antibodies production, diabetes development, and treatment of this disease. Methodology: This observational study included 200 Covid-19 patients in privet centers from January 1, 2021 to January 1, 2022. All patients had fasting blood sugars and anti-Covid-19antibodies. Anthropometric parameters were measured in all participants. Results: The patients were divided into two groups according to body weight; normal body weight (50) and excess body weight (150). There was a significant difference between them regarding age. Diabetes mellitus developed in 20% of normal weight patients while 80% of excess weight patients had diabetes (p=0.0001). Antibodies production (IgM and IgG) occurred in normal weight patients (90% and 98%, respectively). Only 4% patients with normal weight needed oxygen therapy while 93.33% of obese patients required oxygen therapy.Conclusions: Obesity increased the development of diabetes, decrease antibodies production and increase requirement for oxygen therapy in Covid-19 patients.