Onychomycosis: Old and New

被引：33

作者：

Bermudez, Narges Maskan ^{[1
]}

Rodriguez-Tamez, Giselle ^{[2
]}

Perez, Sofia ^{[1
]}

Tosti, Antonella ^{[1
]}

机构：

[1] Univ Miami, Miller Sch Med, Dr Philip Frost Dept Dermatol & Cutaneous Surg, Miami, FL 33125 USA

[2] Univ Autonoma Nuevo Leon, Univ Hosp Dr Jose Eleuterio Gonzalez, Dermatol Dept, Monterrey 64460, Mexico

来源：

JOURNAL OF FUNGI | 2023年 / 9卷 / 05期

关键词：

onychomycosis; dermatophyte; dermoscopy; fungal culture; fungal nail infection; nondermatophyte; yeast; DERMATOPHYTE TOENAIL ONYCHOMYCOSIS; DOUBLE-BLIND; CONTINUOUS TERBINAFINE; NAIL LACQUER; INTERMITTENT ITRACONAZOLE; UNSUSPECTED ONYCHOMYCOSIS; SUBUNGUAL ONYCHOMYCOSIS; PARALLEL-GROUP; SINGLE-BLIND; RISK-FACTORS;

D O I：

10.3390/jof9050559

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Onychomycosis is a common chronic fungal infection of the nail that causes discoloration and/or thickening of the nail plate. Oral agents are generally preferred, except in the case of mild toenail infection limited to the distal nail plate. Terbinafine and itraconazole are the only approved oral therapies, and fluconazole is commonly utilized off-label. Cure rates with these therapies are limited, and resistance to terbinafine is starting to develop worldwide. In this review, we aim to review current oral treatment options for onychomycosis, as well as novel oral drugs that may have promising results in the treatment of onychomycosis.

引用

页数：13

共 103 条

[1] Methylene blue vs methyl aminolevulinate photodynamic therapy in combination with oral terbinafine in the treatment of severe dermatophytic toenail onychomycosis: Short- and long-term effects [J].