Current concept of low-grade serous ovarian carcinoma

被引:1
作者
Nakayama, Kentaro [1 ,4 ]
Razia, Sultana [2 ]
Ishibashi, Tomoka [1 ]
Kyo, Satoru [3 ]
机构
[1] Nagoya City Univ East Med Ctr, Dept Obstet & Gynecol, Nagoya, Japan
[2] Shimane Univ, Sch Med, Dept Legal Med, Izumo, Japan
[3] Shimane Univ, Sch Med, Dept Obstet & Gynecol, Izumo, Japan
[4] Nagoya City Univ East Med Ctr, Dept Obstet & Gynecol, 1 Chome 2-23 Wakamizu,Chikusa Ku, Nagoya, Aichi 4648547, Japan
关键词
Genetic alterations; low-grade serous ovarian carcinoma (LGSOC); MAPK pathway; molecular targeted therapy; overall survival (OS); MEK INHIBITOR; COMBINATION;
D O I
10.21037/tcr-23-1161
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
引用
收藏
页码:6 / 10
页数:5
相关论文
共 24 条
[1]   EMR 20006-012: A phase II randomized double-blind placebo controlled trial comparing the combination of pimasertib (MEK inhibitor) with SAR245409 (PI3K inhibitor) to pimasertib alone in patients with previously treated unresectable borderline or low grade ovarian cancer [J].
Arend, Rebecca C. ;
Davis, Allison M. ;
Chimiczewski, Przemyslaw ;
O'Malley, David M. ;
Provencher, Diane ;
Vergote, Ignace ;
Ghamande, Sharad ;
Birrer, Michael J. .
GYNECOLOGIC ONCOLOGY, 2020, 156 (02) :301-307
[2]   Molecular features as promising biomarkers in ovarian cancer [J].
Buklaho, Patrycja Aleksandra ;
Kisluk, Joanna ;
Wasilewska, Natalia ;
Niklinski, Jacek .
ADVANCES IN CLINICAL AND EXPERIMENTAL MEDICINE, 2023, 32 (09) :1029-1040
[3]   Selumetinib in women with recurrent low-grade serous carcinoma of the ovary or peritoneum: an open-label, single-arm, phase 2 study [J].
Farley, John ;
Brady, William E. ;
Vathipadiekal, Vinod ;
Lankes, Heather A. ;
Coleman, Robert ;
Morgan, Mark A. ;
Mannel, Robert ;
Yamada, S. Diane ;
Mutch, David ;
Rodgers, William H. ;
Birrer, Michael ;
Gershenson, David M. .
LANCET ONCOLOGY, 2013, 14 (02) :134-140
[4]   NOTCH Signaling Limits the Response of Low-Grade Serous Ovarian Cancers to MEK Inhibition [J].
Fernandez, Marta Llaurado ;
Hijmans, E. Marielle ;
Gennissen, Annemiek M. C. ;
Wong, Nelson K. Y. ;
Li, Shang ;
Wisman, G. Bea A. ;
Hamilton, Aleksandra ;
Hoenisch, Joshua ;
Dawson, Amy ;
Lee, Cheng -Han ;
Bittner, Madison ;
Kim, Hannah ;
DiMattia, Gabriel E. ;
Lok, Christianne A. R. ;
Lieftink, Cor ;
Beijersbergen, Roderick L. ;
de Jong, Steven ;
Carey, Mark S. ;
Bernards, Rene ;
Berns, Katrien .
MOLECULAR CANCER THERAPEUTICS, 2022, 21 (12) :1862-1874
[5]   The genomic landscape of low-grade serous ovarian/peritoneal carcinoma and its impact on clinical outcomes [J].
Gershenson, David M. ;
Sun, Charlotte C. ;
Westin, Shannon N. ;
Eyada, Mostafa ;
Cobb, Lauren P. ;
Nathan, Lisa C. ;
Sood, Anil K. ;
Malpica, Anais ;
Hillman, Robert T. ;
Wong, Kwong K. .
GYNECOLOGIC ONCOLOGY, 2022, 165 (03) :560-567
[6]   Trametinib versus standard of care in patients with recurrent low-grade serous ovarian cancer (GOG 281/LOGS): an international, randomised, open-label, multicentre, phase 2/3 trial [J].
Gershenson, David M. ;
Miller, Austin ;
Brady, William E. ;
Paul, James ;
Carty, Karen ;
Rodgers, William ;
Millan, David ;
Coleman, Robert L. ;
Moore, Kathleen N. ;
Banerjee, Susana ;
Connolly, Kate ;
Secord, Angeles Alvarez ;
O'Malley, David M. ;
Dorigo, Oliver ;
Gaillard, Stephanie ;
Gabra, Hani ;
Slomovitz, Brian ;
Hanjani, Parviz ;
Farley, John ;
Churchman, Michael ;
Ewing, Ailith ;
Hollis, Robert L. ;
Herrington, C. Simon ;
Huang, Helen Q. ;
Wenzel, Lari ;
Gourley, Charlie .
LANCET, 2022, 399 (10324) :541-553
[7]   Impact of mutational status on survival in low-grade serous carcinoma of the ovary or peritoneum [J].
Gershenson, David M. ;
Sun, Charlotte C. ;
Wong, Kwong-Kwok .
BRITISH JOURNAL OF CANCER, 2015, 113 (09) :1254-1258
[8]   Hormonal therapy for recurrent low-grade serous carcinoma of the ovary or peritoneum [J].
Gershenson, David M. ;
Sun, Charlotte C. ;
Iyer, Revathy B. ;
Malpica, Anais L. ;
Kavanagh, John J. ;
Bodurka, Diane C. ;
Schmeler, Kathleen ;
Deavers, Michael .
GYNECOLOGIC ONCOLOGY, 2012, 125 (03) :661-666
[9]   Recurrent low-grade serous ovarian carcinoma is relatively chemoresistant [J].
Gershenson, David M. ;
Sun, Charlotte C. ;
Bodurka, Diane ;
Coleman, Robert L. ;
Lu, Karen H. ;
Sood, Anil K. ;
Deavers, Michael ;
Malpica, Anais L. ;
Kavanagh, John J. .
GYNECOLOGIC ONCOLOGY, 2009, 114 (01) :48-52
[10]   Extreme Outlier Analysis Identifies Occult Mitogen-Activated Protein Kinase Pathway Mutations in Patients With Low-Grade Serous Ovarian Cancer [J].
Grisham, Rachel N. ;
Sylvester, Brooke E. ;
Won, Helen ;
McDermott, Gregory ;
DeLair, Deborah ;
Ramirez, Ricardo ;
Yao, Zhan ;
Shen, Ronglai ;
Dao, Fanny ;
Bogomolniy, Faina ;
Makker, Vicky ;
Sala, Evis ;
Soumerai, Tara E. ;
Hyman, David M. ;
Socci, Nicholas D. ;
Viale, Agnes ;
Gershenson, David M. ;
Farley, John ;
Levine, Douglas A. ;
Rosen, Neal ;
Berger, Michael F. ;
Spriggs, David R. ;
Aghajanian, Carol A. ;
Solit, David B. ;
Iyer, Gopa .
JOURNAL OF CLINICAL ONCOLOGY, 2015, 33 (34) :4099-+