Hemophagocytic lymphohistiocytosis due to disseminated histoplasmosis in a patient with HIV infection

被引：5

作者：

Divyashree, Krishna ^{[1
]}

Singh, Harpreet ^{[4
]}

Parkhi, Mayur ^{[2
]}

Karmakar, Indrani ^{[3
]}

Sachdeva, Man Updesh Singh ^{[3
]}

Suri, Vikas

Bhalla, Ashish

机构：

[1] Post Grad Inst Med Educ & Res, Dept Internal Med, Chandigarh, India

[2] Post Grad Inst Med Educ & Res, Dept Histopathol, Chandigarh, India

[3] Post Grad Inst Med Educ & Res, Dept Hematol, Chandigarh, India

[4] Nehru Hosp, Post Grad Inst Med Educ & Res, Dept Internal Med, 4th Floor, Chandigarh 160012, India

来源：

JOURNAL OF GLOBAL INFECTIOUS DISEASES | 2023年 / 15卷 / 03期

关键词：

CD4; count; disseminated histoplasmosis; hemophagocytic lymphohistiocytosis; HIV; Mycobacterium tuberculosis; pyrexia of unknown origin; GUIDELINES;

D O I：

10.4103/jgid.jgid_190_22

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

Hemophagocytic lymphohistiocytosis is usually considered a rapidly progressive fatal illness with poor outcomes. It is of two types: primary or familial and secondary. In patients with HIV, opportunistic infections are the secondary triggers of HLH. First line of management of infection associated HLH is treatment of the underlying infection. Here, we present a case of HLH in HIV infection due to disseminated histoplasmosis managed with liposomal amphotericin B, who required immunosuppressive therapy with intravenous immunoglobulin and dexamethasone due to nonresponse to primary therapy.

引用

页码：124 / 126

页数：3

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