A fatal course of COVID-19 during the Omicron surge: can you estimate your patients' SARS-CoV-2 immune status?

被引：0
|
作者：
Mersch, Martin [1 ]
Schlabe, Stefan [1 ,2 ]
Breitschwerdt, Sven [1 ,2 ]
Laufenberg, Judith [1 ,2 ]
Emmert, Dorian [3 ]
Aldabbagh, Souhaib [3 ]
Boesecke, Christoph [1 ,2 ]
Monin, Malte Benedikt [1 ,2 ]
机构：
[1] Univ Hosp Bonn, Dept Internal Med 1, Venusberg Campus 1, D-53127 Bonn, Germany
[2] German Ctr Infect Res DZIF, Partner Site Cologne Bonn, Bonn, Germany
[3] Bonn Univ Hosp, Inst Virol, Bonn, Germany
来源：
INFECTION | 2024年 / 52卷 / 01期
关键词：
COVID-19; Omicron variant of concern; Severe course; Immune status;
D O I：
10.1007/s15010-023-02120-w
中图分类号：
R51 [传染病];
学科分类号：
100401 ;
摘要：
We present a case of an ultimately fatal course of COVID-19 (coronavirus disease-19) in an 81-year-old female patient during the Omicron surge. The patient did not represent the typical patient at risk for severe COVID-19 with significant causes of immunodeficiency. However, she had been skeptical about the vaccination for severe acute respiratory syndrome virus-2 (SARS-CoV-2) and had refused it. Moreover, there had been no previous COVID-19 episodes. Our case report illustrates that with regard to SARS-CoV-2, immunologically naive patients are still at risk for severe and/or even fatal courses of COVID-19. We call to implement both, recommendations for SARS-CoV-2 vaccinations as well as for antiviral treatment.
引用
收藏
页码：271 / 273
页数：3
相关论文
共 50 条
  • [11] Rise of Neurologic Manifestations During SARS-CoV-2 Omicron Wave in Children With COVID-19
    Dimopoulou, Dimitra
    Dasoula, Foteini
    Liaska, Marianthi
    Eleftheriou, Irini
    Maritsi, Despoina
    Tsolia, Maria
    Vartzelis, George
    PEDIATRIC INFECTIOUS DISEASE JOURNAL, 2023, 42 (04) : E128 - E129
  • [12] Sex differences in immune responses to SARS-CoV-2 in patients with COVID-19
    Zhao, Guolian
    Xu, Yazhou
    Li, Jing
    Cui, Xiaoli
    Tan, Xiaowen
    Zhang, Hongyue
    Dang, Liyun
    BIOSCIENCE REPORTS, 2021, 41 (01)
  • [13] The interplay between the immune system and SARS-CoV-2 in COVID-19 patients
    Shabbir, Sana
    Raza, Muhammad Hassan
    Arshad, Muhammad
    Khan, Muhammad Jawad
    ARCHIVES OF VIROLOGY, 2021, 166 (08) : 2109 - 2117
  • [14] The interplay between the immune system and SARS-CoV-2 in COVID-19 patients
    Sana Shabbir
    Muhammad Hassan Raza
    Muhammad Arshad
    Muhammad Jawad Khan
    Archives of Virology, 2021, 166 : 2109 - 2117
  • [15] SARS-CoV-2, COVID-19 and the aging immune system
    Bartleson, Juliet M.
    Radenkovic, Dina
    Covarrubias, Anthony J.
    Furman, David
    Winer, Daniel A.
    Verdin, Eric
    NATURE AGING, 2021, 1 (09): : 769 - 782
  • [16] SARS-CoV-2, COVID-19 and the aging immune system
    Juliet M. Bartleson
    Dina Radenkovic
    Anthony J. Covarrubias
    David Furman
    Daniel A. Winer
    Eric Verdin
    Nature Aging, 2021, 1 : 769 - 782
  • [17] Status of SARS-CoV-2 in cerebrospinal fluid of patients with COVID-19 and stroke
    Al Saiegh, Fadi
    Ghosh, Ritam
    Leibold, Adam
    Avery, Michael B.
    Schmidt, Richard F.
    Theofanis, Thana
    Mouchtouris, Nikolaos
    Philipp, Lucas
    Peiper, Stephen C.
    Wang, Zi-Xuan
    Rincon, Fred
    Tjoumakaris, Stavropoula, I
    Jabbour, Pascal
    Rosenwasser, Robert H.
    Gooch, M. Reid
    JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, 2020, 91 (08): : 846 - 848
  • [18] SARS-CoV-2 Sequence Analysis during COVID-19 Case Surge, Liberia, 2021
    Shobayo, Bode
    Mishra, Mitali
    Sameroff, Stephen
    Petrosov, Alexandra
    Ng, James
    Gokden, Alper
    MaCauley, Jane
    Jain, Komal
    Renken, Courtney
    Duworko, James Tanu
    Badio, Moses
    Jallah, Wilhemina
    Hensley, Lisa
    Briese, Thomas
    Lipkin, W. Ian
    Mishra, Nischay
    EMERGING INFECTIOUS DISEASES, 2021, 27 (12) : 3185 - 3188
  • [19] Epidemiology of SARS-CoV-2/COVID-19 Current status
    Salzberger, B.
    Buder, F.
    Lampl, B. T.
    Ehrenstein, B.
    Hitzenbichler, F.
    Holzmann, T.
    Schmidt, B.
    Hanses, F.
    GASTROENTEROLOGE, 2020, 15 (06): : 443 - 451
  • [20] COVID-19 severity from Omicron and Delta SARS-CoV-2 variants
    Wrenn, Jesse O.
    Pakala, Suman B.
    Vestal, Grant
    Shilts, Meghan H.
    Brown, Hunter M.
    Bowen, Sara M.
    Strickland, Britton A.
    Williams, Timothy
    Mallal, Simon A.
    Jones, Ian D.
    Schmitz, Jonathan E.
    Self, Wesley H.
    Das, Suman R.
    INFLUENZA AND OTHER RESPIRATORY VIRUSES, 2022, 16 (05) : 832 - 836
12345