The genetic background of pediatric acute myeloid leukemia (AML) does not fit with classification systems developed for adult AML. This study investigates the genetic background of pediatric AML and proposes a genomic framework for improved classification and risk stratification based on the driver alterations.
机构:
Ohio State Univ, Clara D Bloomfield Ctr Leukemia Outcomes Res, Columbus, OH 43210 USAErasmus MC, Cell Biol, Sophia Childrens Hosp, Rotterdam, Netherlands
Nicolet, Deedra
Mrozek, Krzysztof
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Ohio State Univ, Clara D Bloomfield Ctr Leukemia Outcomes Res, Comprehens Canc Ctr, Columbus, OH 43210 USAErasmus MC, Cell Biol, Sophia Childrens Hosp, Rotterdam, Netherlands
Mrozek, Krzysztof
Kolitz, Jonathan E.
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Northwell Hlth, Monter Canc Ctr, North Shore Univ Hosp, New Hyde Pk, NY USA
Northwell Hlth, Long Isl Jewish Med Ctr, New Hyde Pk, NY USAErasmus MC, Cell Biol, Sophia Childrens Hosp, Rotterdam, Netherlands
机构:
St Jude Childrens Res Hosp, Dept Oncol, Memphis, TN USA
St Jude Childrens Res Hosp, 262 Danny Thomas Pl,Mail Stop 260, Memphis, TN 38105 USASt Jude Childrens Res Hosp, Dept Oncol, Memphis, TN USA
Karol, Seth E.
Gueguen, Gwenaelle
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Robert Debre Univ Hosp, AP HP, Ctr Clin Invest, INSERM,CIC1426, Paris, FranceSt Jude Childrens Res Hosp, Dept Oncol, Memphis, TN USA
机构:
Univ Ulsan, Coll Med, Dept Pediat, Asan Med Ctr,Childrens Hosp, Seoul, South KoreaUniv Ulsan, Coll Med, Dept Pediat, Asan Med Ctr,Childrens Hosp, Seoul, South Korea
机构:
Childrens Hosp Michigan, Div Pediat Hematol Oncol, 3901 Beaubien St, Detroit, MI 48201 USAChildrens Hosp Michigan, Div Pediat Hematol Oncol, 3901 Beaubien St, Detroit, MI 48201 USA
Gallardo, Maria S.
Joyrich, Richard
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Wayne State Univ, Karmanos Canc Inst, Dept Hematol Oncol, Detroit, MI USAChildrens Hosp Michigan, Div Pediat Hematol Oncol, 3901 Beaubien St, Detroit, MI 48201 USA
Joyrich, Richard
Taub, Jeffrey W.
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Childrens Hosp Michigan, Div Pediat Hematol Oncol, 3901 Beaubien St, Detroit, MI 48201 USA
Cent Michigan Univ, Coll Med, Discipline Pediat, Detroit, MI USA
Wayne State Univ, Sch Med, Dept Pediat, Detroit, MI USAChildrens Hosp Michigan, Div Pediat Hematol Oncol, 3901 Beaubien St, Detroit, MI 48201 USA