The marriage of coherent Raman scattering imaging and advanced computational tools

被引:4
作者
Peterson, Walker [1 ]
Hiramatsu, Kotaro [1 ,2 ]
Goda, Keisuke [1 ,3 ,4 ,5 ]
机构
[1] Univ Tokyo, Dept Chem, Tokyo 1130033, Japan
[2] Univ Tokyo, Res Ctr Spectrochem, Tokyo 1130033, Japan
[3] Univ Calif Los Angeles, Dept Bioengn, Los Angeles, CA 90095 USA
[4] Wuhan Univ, Inst Technol Sci, Wuhan 430072, Hubei, Peoples R China
[5] LucasLand Inc, Tokyo 1010052, Japan
关键词
SPECTROSCOPY; DOMAIN;
D O I
10.1038/s41377-023-01160-z
中图分类号
O43 [光学];
学科分类号
070207 ; 0803 ;
摘要
Coherent Raman scattering microscopy can provide high-contrast tissue and single-cell images based on the inherent molecular vibrations of the sample. However, conventional techniques face a three-way trade-off between Raman spectral bandwidth, imaging speed, and image fidelity. Although currently challenging to address via optical design, this trade-off can be overcome via emerging computational tools such as compressive sensing and machine learning.
引用
收藏
页数:3
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