Investigator- and patient-rated local tolerability in phase 3 trials of topical roflumilast in patients with psoriasis, seborrheic dermatitis, and atopic dermatitis

被引：0

作者：

Bunick, Christopher G. ^{[1
,2
]}

Bhatia, Neal ^{[3
]}

Del Rosso, James ^{[4
]}

Draelos, Zoe D. ^{[5
]}

Eichenfield, Lawrence F. ^{[6
]}

Kircik, Leon H. ^{[7
,8
,9
,10
]}

Lebwohl, Mark G. ^{[7
]}

Gooderham, Melinda ^{[11
,12
]}

Green, Lawrence J.

Hebert, Adelaide A. ^{[14
]}

Vender, Ronald B. ^{[15
]}

Zirwas, Matthew ^{[16
,17
]}

Simpson, Eric L. ^{[13
,18
]}

Gold, Linda Stein ^{[19
]}

Seal, Melissa ^{[20
]}

Snyder, Scott ^{[20
]}

Osborne, David W. ^{[20
]}

Burnett, Patrick ^{[20
]}

Higham, Robert C. ^{[20
]}

Chu, David H. ^{[20
]}

Berk, David R. ^{[20
]}

机构：

[1] Yale Univ, Dept Dermatol, New Haven, CT USA

[2] Yale Univ, Program Translat Biomed, New Haven, CT USA

[3] Therapeut Clin Res, San Diego, CA USA

[4] JDR Dermatol Res, Las Vegas, NV USA

[5] Dermatol Consulting Serv, High Point, NC USA

[6] Univ Calif San Diego, Radys Childrens Hosp San Diego, Dept Dermatol & Pediat, San Diego, CA USA

[7] Icahn Sch Med Mt Sinai, New York, NY USA

[8] Indiana Med Ctr, Indianapolis, IN USA

[9] Phys Skin Care PLLC, Louisville, KY USA

[10] Skin Sci PLLC, Louisville, KY USA

[11] SkiN Ctr Dermatol, Prob Med Res, Peterborough, ON, Canada

[12] Queens Univ, Peterborough, ON, Canada

[13] George Washington Univ, Sch Med, Rockville, MD USA

[14] UT Hlth McGovern Med Sch, Houston, TX USA

[15] Dermatrials Res Inc, Hamilton, ON, Canada

[16] Dermatologists Cent States, Prob Med Res, Bexley, OH USA

[17] Ohio Univ, Bexley, OH USA

[18] Oregon Hlth & Sci Univ, Portland, OR USA

[19] Henry Ford Med Ctr, Detroit, MI USA

[20] Arcutis Biotherapeut Inc, Westlake Village, CA USA

来源：

BRITISH JOURNAL OF DERMATOLOGY | 2024年 / 190卷

关键词：

topical roflumilast; atopic dermatitis; psoriasis; seborrheic dermatitis; local tolerability;

D O I：

10.1093/bjd/ljad498.012

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

504

引用

页码：II9 / II10

页数：2

共 25 条

[1] Investigator- and patient-rated local tolerability in phase 3 trials of topical roflumilast in patients with psoriasis, seborrheic dermatitis, and atopic dermatitis
Bunick, Christopher G.
Bhatia, Neal
Del Rosso, James
Draelos, Zoe D.
Eichenfield, Lawrence F.
Kircik, Leon H.
Lebwohl, Mark G.
Gooderham, Melinda
Green, Lawrence J.
Hebert, Adelaide A.
Vender, Ronald B.
Zirwas, Matthew
Simpson, Eric L.
Gold, Linda Stein
Seal, Melissa
Snyder, Scott
Osborne, David W.
Burnett, Patrick
Higham, Robert C.
Chu, David H.
Berk, David R.
BRITISH JOURNAL OF DERMATOLOGY, 2024, 191
[2] Efficacy and safety of roflumilast foam 0.3% in patients with seborrheic dermatitis in a phase 3 trial: assessment of pruritus
Blauvelt, Andrew
Draelos, Zoe D.
Gooderham, Melinda
Lain, Edward
Moore, Angela Y.
Papp, Kim A.
Zirwas, Matthew
Krupa, David
Burnett, Patrick
Berk, David R.
Chu, David H.
BRITISH JOURNAL OF DERMATOLOGY, 2023, 188
[3] Nonclinical Safety and Toxicokinetics of MnTE-2-PyP (BMX-010), a Topical Agent in Phase 2 Trials for Psoriasis and Atopic Dermatitis
Gad, Shayne C.
Sullivan, Dexter W., Jr.
Mujer, Cesar V.
Spainhour, Charles B.
Crapo, James D.
INTERNATIONAL JOURNAL OF TOXICOLOGY, 2019, 38 (04) : 291 - 302
[4] Roflumilast foam 0.3% for adolescent and adult patients with seborrheic dermatitis: A randomized, double-blinded, vehicle-controlled, phase 3 trial
Blauvelt, Andrew
Draelos, Zoe D.
Gold, Linda Stein
Alonso-Llamazares, Javier
Bhatia, Neal
DuBois, Janet
Forman, Seth B.
Gooderham, Melinda
Green, Lawrence
Guenthner, Scott T.
Hebert, Adelaide A.
Lain, Edward
Moore, Angela Y.
Papp, Kim A.
Zirwas, Matthew
Kato, Saori
Snyder, Scott
Krupa, David
Burnett, Patrick
Berk, David R.
Chu, David H.
JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, 2024, 90 (05) : 986 - 993
[5] Once-daily roflumilast cream 0.15% for atopic dermatitis: pooled results from INTEGUMENT-1/2 phase 3 trials
Eichenfield, Lawrence F.
Boguniewicz, Mark
Simpson, Eric L.
Blauvelt, Andrew
Gooderham, Melinda
Lain, Edward
Chu, David H.
Higham, Robert C.
BRITISH JOURNAL OF DERMATOLOGY, 2024, 190 : II10 - II11
[6] Tapinarof Improved Outcomes and Sleep for Patients and Families in Two Phase 3 Atopic Dermatitis Trials in Adults and Children
Simpson, Eric L.
Hebert, Adelaide A.
Browning, John
Serrao, Rocco T.
Sofen, Howard
Brown, Philip M.
Piscitelli, Stephen C.
Rubenstein, David S.
Tallman, Anna M.
DERMATOLOGY AND THERAPY, 2025, 15 (01) : 111 - 124
[7] Pooled efficacy, patient-reported outcomes, and safety of roflumilast cream 0.15% from the INTEGUMENT-1 and INTEGUMENT-2 phase 3 trials of adults and children with atopic dermatitis
Simpson, Eric
Boguniewicz, Mark
Eichenfield, Lawrence
Gonzales, Mercedes E.
Hebert, Adelaide A.
Prajapati, Vimal H.
Gooderham, Melinda
Krupa, David
Chu, David H.
Higham, Robert C.
Berk, David R.
BRITISH JOURNAL OF DERMATOLOGY, 2024, 191
[8] Baricitinib improves symptoms in patients with moderate-to-severe atopic dermatitis and inadequate response to topical corticosteroids: patient-reported outcomes from two randomized monotherapy phase III trials
Reich, K.
DeLozier, A. M.
Nunes, F. P.
Thyssen, J. P.
Eichenfield, L. F.
Wollenberg, A.
Terres, J. A. Ross
Watts, S. D.
Chen, Y-F
Simpson, E. L.
Silverberg, J., I
JOURNAL OF DERMATOLOGICAL TREATMENT, 2022, 33 (03) : 1521 - 1530
[9] Tralokinumab Efficacy and Safety, with or without Topical Corticosteroids, in North American Adults with Moderate-to-Severe Atopic Dermatitis: A Subanalysis of Phase 3 Trials ECZTRA 1, 2, and 3
Blauvelt, Andrew
Gooderham, Melinda
Bhatia, Neal
Langley, Richard G.
Schneider, Shannon
Zoidis, John
Kurbasic, Azra
Armstrong, April
Silverberg, Jonathan, I
DERMATOLOGY AND THERAPY, 2022, 12 (11) : 2499 - 2516
[10] Tralokinumab Efficacy and Safety, with or without Topical Corticosteroids, in North American Adults with Moderate-to-Severe Atopic Dermatitis: A Subanalysis of Phase 3 Trials ECZTRA 1, 2, and 3
Andrew Blauvelt
Melinda Gooderham
Neal Bhatia
Richard G. Langley
Shannon Schneider
John Zoidis
Azra Kurbasic
April Armstrong
Jonathan I. Silverberg
Dermatology and Therapy, 2022, 12 : 2499 - 2516

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