Evolving Diagnostic and Management Advances in Coronary Heart Disease

被引：15

作者：

Ribeiro, Matheus de Oliveira Laterza ^{[1
]}

Correia, Vinicius Machado ^{[1
]}

de Oliveira, Lucas Lentini Herling ^{[1
]}

Soares, Paulo Rogerio ^{[1
]}

Scudeler, Thiago Luis ^{[1
]}

机构：

[1] Univ Sao Paulo, Inst Coracao InCor, Hosp Clin, Fac Med, BR-05403010 Sao Paulo, Brazil

来源：

LIFE-BASEL | 2023年 / 13卷 / 04期

关键词：

coronary artery disease; coronary intervention; atherosclerosis; FRACTIONAL FLOW RESERVE; ACUTE MYOCARDIAL-INFARCTION; ELUTING STENT IMPLANTATION; WAVE-FREE RATIO; NEAR-INFRARED SPECTROSCOPY; TREATING DE-NOVO; INTRAVASCULAR ULTRASOUND; ROTATIONAL ATHERECTOMY; COMPUTED-TOMOGRAPHY; PROGENITOR CELLS;

D O I：

10.3390/life13040951

中图分类号：

Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Despite considerable improvement in diagnostic modalities and therapeutic options over the last few decades, the global burden of ischemic heart disease is steadily rising, remaining a major cause of death worldwide. Thus, new strategies are needed to lessen cardiovascular events. Researchers in different areas such as biotechnology and tissue engineering have developed novel therapeutic strategies such as stem cells, nanotechnology, and robotic surgery, among others (3D printing and drugs). In addition, advances in bioengineering have led to the emergence of new diagnostic and prognostic techniques, such as quantitative flow ratio (QFR), and biomarkers for atherosclerosis. In this review, we explore novel diagnostic invasive and noninvasive modalities that allow a more detailed characterization of coronary disease. We delve into new technological revascularization procedures and pharmacological agents that target several residual cardiovascular risks, including inflammatory, thrombotic, and metabolic pathways.

引用

页数：27

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