Neuro-inspired thermoresponsive nociceptor for intelligent sensory systems

Artificial nociceptors with biologically complex sensory functions show intriguing potential in the growing fields of humanoid robotics and intelligent prosthetics. However, conventional artificial sensory systems with sepa-ration of sensors, memory, and processing units pose serious challenges in terms of device integration, efficiency, and power consumption. Here we demonstrate a neuro-inspired artificial electronic receptor prototype based on a bismuth selenide (Bi2Se3) memristor for a highly efficient artificial thermal nociception system. Bi2Se3 ther-moelectric films as functional materials enable the memristor to have in-situ temperature sensing, internal storage, and computing capabilities. Ag/PMMA/Bi2Se3/ITO memristor-based electronic receptors can reproduce the "threshold", "relaxation", and "no adaptation" behaviors of human nociceptors according to the intensity, duration, and repetitions of external stimuli. Further combining this artificial receptor with a robotic manipu-lator can be used to construct an artificial thermal nociception system and successfully demonstrate the nerve reflex action under thermal stimulation. The designed and realized highly efficient artificial nociceptors will enable novel sensing paradigms in biomimetic applications and neuromorphic engineering.