Multi-institutional assessment of the prevalence of neuroendocrine tumors in children undergoing laparoscopic appendectomy for acute appendicitis in the United States

被引：4

作者：

Zeineddin, Suhail ^{[1
,9
]}

Aldrink, Jennifer H. H. ^{[2
]}

Bering, Jakob ^{[2
]}

Hoyt, David W. W. ^{[3
]}

Kastenberg, Zachary J. J. ^{[3
]}

Brungardt, Joseph ^{[4
]}

Dasgupta, Roshni ^{[4
]}

Rinehardt, Hannah N. N. ^{[5
]}

Malek, Marcus M. M. ^{[5
]}

Ziogas, Ioannis A. A. ^{[6
]}

Roach, Jonathan P. P. ^{[6
]}

Craig, Brian T. T. ^{[7
]}

Rothstein, David H. H. ^{[8
]}

Lautz, Timothy B. B. ^{[1
]}

机构：

[1] Northwestern Univ, Ann & Robert H Lurie Childrens Hosp Chicago, Div Pediat Surg, Chicago, IL USA

[2] Ohio State Univ, Nationwide Childrens Hosp, Dept Surg, Div Pediat Surg,Coll Med, Columbus, OH USA

[3] Univ Utah, Primary Childrens Hosp, Dept Surg, Div Pediat Surg, Salt Lake City, UT USA

[4] Univ Cincinnati, Cincinnati Childrens Med Ctr, Div Pediat Gen & Thorac Surg, Cincinnati, OH USA

[5] Univ Pittsburgh, Childrens Hosp Pittsburgh, Dept Surg, Div Pediat Gen & Thorac Surg,Med Ctr, Pittsburgh, PA USA

[6] Univ Colorado, Childrens Hosp Colorado, Dept Surg, Div Pediat Surg,Sch Med, Aurora, CO USA

[7] Med Coll Wisconsin, Dept Surg, Div Pediat Surg, Childrens Wisconsin, Milwaukee, WI USA

[8] Univ Washington, Seattle Childrens Hosp, Div Pediat Gen & Thorac Surg, Seattle, WA USA

[9] 420 E Ohio St,Apt 34F, Chicago, IL 60611 USA

来源：

PEDIATRIC BLOOD & CANCER | 2024年 / 70卷 / 11期

关键词：

appendectomy; appendicitis; carcinoid; NET; neuroendocrine tumor; SURGICAL-MANAGEMENT; EXPERIENCE; PATHOLOGY; CHILDHOOD;

D O I：

10.1002/pbc.30620

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

As non-operative management of acute appendicitis in children has become more common, missed incidental appendiceal pathology can be an unintended consequence. We assessed the prevalence of neuroendocrine tumors in appendectomy specimens from eight US children's hospitals from 2012 to 2021. The prevalence of neuroendocrine tumors (NET) was found to be 1:271, with a median age of 14 years and 62% female. Most tumors were small (median 6 mm; interquartile range [IQR]: 3-10), and no recurrence was noted during the follow-up period (median 22.5 months; IQR: 3-53). The possibility of delayed diagnosis of these tumors should be part of the discussion for non-operative management of pediatric acute appendicitis.

引用

页数：4

共 1 条

[1] Delaying Appendectomy Does Not Lead to Higher Rates of Surgical Site Infections A Multi-institutional Analysis of Children With Appendicitis
Boomer, Laura A.
Cooper, Jennifer N.
Anandalwar, Seema
Fallon, Sara Childress
Ostlie, Daniel
Leys, Charles M.
Rangel, Shawn
Mattei, Peter
Sharp, Susan W.
St Peter, Shawn D.
Rodriguez, J. Ruben
Kenney, Brian
Besner, Gail E.
Deans, Katherine J.
Minneci, Peter C.
ANNALS OF SURGERY, 2016, 264 (01) : 164 - 168

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