Preliminary Effects of an Urban Gardens and Peer Nutritional Counseling Intervention on HIV Treatment Adherence and Detectable Viral Load Among People with HIV and Food Insecurity: Evidence from a Pilot Cluster Randomized Controlled Trial in the Dominican Republic

被引:7
|
作者
Derose, Kathryn P. [1 ,2 ]
Then-Paulino, Amarilis [3 ,4 ]
Han, Bing [5 ,6 ]
Armenta, Gabriela [7 ]
Palar, Kartika [8 ]
Jimenez-Paulino, Gipsy [3 ]
Sheira, Lila A. [8 ]
Acevedo, Ramon [9 ]
Fulcar, Maria A. [10 ]
Bernard, Claudio Lugo [3 ]
Camacho, Isidro Veloz [3 ]
Donastorg, Yeycy [11 ]
Wagner, Glenn J. [1 ]
机构
[1] RAND Corp, Behav & Policy Sci Dept, Santa Monica, CA 90401 USA
[2] Univ Massachusetts, Dept Hlth Promot & Policy, 715 N Pleast St, Amherst, MA 01003 USA
[3] Univ Autonoma Santo Domingo, Fac Ciencias Salud, Santo Domingo, Dominican Rep
[4] Minist Salud Publ, Santo Domingo, Dominican Rep
[5] RAND Corp, Econ Sociol & Stat Dept, Santa Monica, CA USA
[6] Kaiser Permanente Southern Calif, Dept Res & Evaluat, Div Biostat Res, Pasadena, CA USA
[7] RAND Corp, Pardee RAND Grad Sch, Santa Monica, CA USA
[8] Univ Calif San Francisco, Div HIV Infect Dis & Global Med, San Francisco, CA 94143 USA
[9] Consejo Nacl VIH & Sida CONAVIHSIDA, Santo Domingo, Dominican Rep
[10] Country Off Dominican Republ, World Food Programme, Santo Domingo, Dominican Rep
[11] Inst Dermatol Dominicano & Cirugia Piel Dr Hubert, Unidad Vacunas & Invest, Santo Domingo, Dominican Rep
基金
美国国家卫生研究院;
关键词
HIV; Food insecurity; Viral suppression; Adherence; Urban gardens; Dominican Republic; ANTIRETROVIRAL THERAPY ADHERENCE; INFECTED INDIVIDUALS; SECURITY; DETERMINANTS; RETENTION; HIV/AIDS; SUPPORT; CARE;
D O I
10.1007/s10461-022-03821-3
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
A pilot cluster randomized controlled trial involving two HIV clinics in the Dominican Republic assessed preliminary efficacy of an urban garden and peer nutritional counseling intervention. A total of 115 participants (52 intervention, 63 control) with moderate or severe food insecurity and sub-optimal antiretroviral therapy (ART) adherence and/or detectable viral load were assessed at baseline, 6- and 12-months. Longitudinal multivariate regression analysis controlling for socio-demographics and accounting for serial cluster correlation found that the intervention: reduced the prevalence of detectable viral load by 20 percentage points at 12 months; reduced any missed clinic appointments by 34 and 16 percentage points at 6 and 12 months; increased the probability of "perfect" ART adherence by 24 and 20 percentage points at 6 and 12 months; and decreased food insecurity at 6 and 12 months. Results are promising and warrant a larger controlled trial to establish intervention efficacy for improving HIV clinical outcomes. Trial registry Clinical Trials Identifier: NCT03568682.
引用
收藏
页码:864 / 874
页数:11
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