The Mediterranean Zoanthid Parazoanthus axinellae as a Novel Source of Antimicrobial Compounds

被引:3
作者
Stabili, Loredana [1 ,2 ,3 ]
Piraino, Stefano [2 ,3 ,4 ]
Rizzo, Lucia [4 ,5 ]
机构
[1] CNR, Inst Water Res, SS Taranto, Via Roma 3, I-74123 Taranto, Italy
[2] Natl Biodivers Future Ctr NBFC, I-90133 Palermo, Italy
[3] Univ Salento, Dept Biol & Environm Sci & Technol, Via Prov Lecce Monteroni, I-72100 Lecce, Italy
[4] Consorzio Nazl Interuniv Sci Mare CoNISMa, Piazzale Flaminio 9, I-00196 Rome, Italy
[5] Natl Res Council CNR, Inst Sci Food Prod, ISPA, Via Prov Lecce Monteroni, I-73100 Lecce, Italy
关键词
Anthozoa; yellow anemone; bioactive compounds; vibrios; antimicrobial activities; ANTIBACTERIAL ACTIVITY; VIBRIO; ANTHOZOA; BACTERIA; INSIGHTS; CNIDARIA; DISEASE; CORALS;
D O I
10.3390/jmse12020354
中图分类号
U6 [水路运输]; P75 [海洋工程];
学科分类号
0814 ; 081505 ; 0824 ; 082401 ;
摘要
Marine bioprospecting is a dynamic research field that explores the oceans and their biodiversity as noteworthy sources of new bioactive compounds. Anthozoans are marine animals belonging to the Cnidaria phylum characterized by highly specialized mechanosensory cells used both for defence against predators and prey capture. Here, high concentration of cnidocysts have been isolated from the Mediterranean zoanthid coral Parazoanthus axinellae (Schmidt, 1862) and their antimicrobial potential has been investigated. The cnidocyst extract exerted significant antibacterial activity against some human pathogens capable of developing resistance to conventional antibiotics such as Streptococcus agalactiae and Coccus sp., and against several Vibrio species, including some microbial strains for humans and farmed fish, such as Vibrio alginolyticus, Vibrio anguillarum, Vibrio fischeri, Vibrio harveyi, and Vibrio vulnificus. Results have been discussed in light of both the ecological aspects and biotechnological value of the cnidocyst extract in the nutritional, nutraceutical, and pharmaceutical fields.
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页数:15
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共 80 条
[51]   Antimicrobial Peptides: A New Hope in Biomedical and Pharmaceutical Fields [J].
Moretta, Antonio ;
Scieuzo, Carmen ;
Petrone, Anna Maria ;
Salvia, Rosanna ;
Manniello, Michele Dario ;
Franco, Antonio ;
Lucchetti, Donatella ;
Vassallo, Antonio ;
Vogel, Heiko ;
Sgambato, Alessandro ;
Falabella, Patrizia .
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY, 2021, 11
[52]   Nanosecond-scale kinetics of nematocyst discharge [J].
Nuechter, Timm ;
Benoit, Martin ;
Engel, Ulrike ;
Oezbek, Suat ;
Holstein, Thomas W. .
CURRENT BIOLOGY, 2006, 16 (09) :R316-R318
[53]   Puncture mechanics of cnidarian cnidocysts: A natural actuator [J].
Oppegard S.C. ;
Anderson P.A. ;
Eddington D.T. .
Journal of Biological Engineering, 3 (1)
[54]   Cnidarian Immunity and the Repertoire of Defense Mechanisms in Anthozoans [J].
Parisi, Maria Giovanna ;
Parrinello, Daniela ;
Stabili, Loredana ;
Cammarata, Matteo .
BIOLOGY-BASEL, 2020, 9 (09) :1-26
[55]   Gone gene fishing: how to catch novel marine antimicrobials [J].
Patrzykat, A ;
Douglas, SE .
TRENDS IN BIOTECHNOLOGY, 2003, 21 (08) :362-369
[56]   3-DIMENSIONAL STRUCTURE OF AN ENZYME MOLECULE [J].
PHILLIPS, DC .
SCIENTIFIC AMERICAN, 1966, 215 (05) :78-&
[57]   To screen or not to screen women for Group B Streptococcus (Streptococcus agalactiae) to prevent early onset sepsis in newborns: recent advances in the unresolved debate [J].
Rao, Guduru Gopal ;
Khanna, Priya .
THERAPEUTIC ADVANCES IN INFECTIOUS DISEASE, 2020, 7
[58]   Population dynamics and zooplankton-predation impact of the indigenous scyphozoan Aurelia aurita and the invasive ctenophore Mnemiopsis leidyi in Limfjorden (Denmark) [J].
Riisgard, Hans Ulrik ;
Madsen, Caroline V. ;
Barth-Jensen, Coralie ;
Purcell, Jennifer E. .
AQUATIC INVASIONS, 2012, 7 (02) :147-162
[59]   The alien species Caulerpa cylindracea and its associated bacteria in the Mediterranean Sea [J].
Rizzo, Lucia ;
Fraschetti, Simonetta ;
Alifano, Pietro ;
Pizzolante, Graziano ;
Stabili, Loredana .
MARINE BIOLOGY, 2016, 163 (01) :1-12
[60]   Association of Vibrio community with the Atlantic Mediterranean invasive alga Caulerpa cylindracea [J].
Rizzo, Lucia ;
Fraschetti, Simonetta ;
Alifano, Pietro ;
Tredici, Maurizio Salvatore ;
Stabili, Loredana .
JOURNAL OF EXPERIMENTAL MARINE BIOLOGY AND ECOLOGY, 2016, 475 :129-136