Rh(I)-catalyzed enantioselective (3+2) transannulations of 1,2,3-thiadiazoles with P-chiral monodentate phosphines

被引：1
作者：
Wei, Hao [1 ]
Chen, Cunzhi [1 ]
Gao, Aijun [2 ,4 ]
Yang, Zhanhui [1 ,3 ]
机构：
[1] Beijing Univ Chem Technol, Coll Chem, Dept Organ Chem, Beijing, Peoples R China
[2] Beijing Univ Chem Technol, Coll Mat Sci & Engn, Beijing, Peoples R China
[3] Beijing Univ Chem Technol, Coll Chem, Dept Organ Chem, Beijing 100029, Peoples R China
[4] Beijing Univ Chem Technol, Coll Mat Sci & Engn, Beijing 100029, Peoples R China
来源：
PHOSPHORUS SULFUR AND SILICON AND THE RELATED ELEMENTS | 2024年 / 199卷 / 02期
基金：
中国国家自然科学基金;
关键词：
Asymmetric catalysis; P-chirality; monodentate phosphines; transannulation; 1,2,3-thiadiazole; RHODIUM-CATALYZED TRANSANNULATION;
D O I：
10.1080/10426507.2023.2281473
中图分类号：
O61 [无机化学];
学科分类号：
070301 ; 081704 ;
摘要：
As a proof of concept, P-chiral monodentate phosphines, which were inactive in promoting the transannulations of 1,2,3-thiadiazoles, were proven viable in the asymmetric catalytic (3 + 2) transannulations of 1,2,3-thiadiazoles with a strained bicyclic alkene. Polycyclic dihydrothiophenes with four newly formed stereocenters are generated in moderate 19-72% yields and 11-27% enantiopurities.
引用
收藏
页码：157 / 161
页数：5
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