The Spatial-Temporal Dimension of Oncological Prevalence and Mortality in Romania

The objective of this study was to identify spatial disparities in the distribution of cancer hotspots within Romania. Additionally, the research aimed to track prevailing trends in cancer prevalence and mortality according to a cancer type. The study covered the timeframe between 2008 and 2017, examining all 3,181 territorial administrative units. The analysis of spatial distribution relied on two key parameters. The first parameter, persistence, measured the duration for which cancer prevalence exceeded the 75th percentile threshold. Cancer prevalence refers to the total number of individuals in a population who have been diagnosed with cancer at a specific time point, including both newly diagnosed cases (occurrence) and existing cases. The second parameter, the time continuity of persistence, calculated the consecutive months during which cancer prevalence consistently surpassed the 75th percentile threshold. Notably, persistence of elevated values was also evident in lowland regions, devoid of any discernible direct connection to environmental conditions. In conclusion, this work bears substantial relevance to regional health policies, by aiding in the formulation of prevention strategies, while also fostering a deeper comprehension of the socioeconomic and environmental factors contributing to cancer. This study presents the inaugural spatial geographical map of cancer fatality and the distribution of high cancer prevalence across all types of cancer in Romania. Conducted between 2008 and 2017, this research aimed to identify patterns in the territorial distribution for all reported cancer within the country's territorial administrative units, by calculation of the two main parameters, namely cancer persistence and the time continuity of its persistence. The findings reveal a decline in total cancer cases, while certain subcategories displayed an upward trend. The analysis of mortality demonstrated a pronounced increase in overall prevalence. By emphasizing the connection between cancer prevalence, outcomes, and geographical factors in Romania, this study provides crucial insights for refining national and European policies in the fight against cancer. This study reveals geographical disparities in the prevalence of all cancer types in RomaniaThe analysis spans the period from 2008 to 2017It was observed that cancer prevalence increased in correlation with anthropogenic interventions in the region