High Prevalence of Candida auris Colonization during Protracted Neonatal Unit South Africa

被引:5
作者
Shuping, Liliwe [1 ,8 ]
Maphanga, Tsidiso G. [1 ]
Naicker, Serisha D. [1 ]
Mpembe, Ruth [1 ]
Ngoma, Nqobile [1 ]
Velaphi, Sithembiso [2 ,3 ]
Nakwa, Firdose [2 ,3 ]
Wadula, Jeannette [3 ,4 ]
Jaglal, Prenika [3 ,4 ]
Govender, Nelesh P. [1 ,3 ,5 ,6 ,7 ]
机构
[1] Natl Inst Communicable Dis, Johannesburg, South Africa
[2] Chris Hani Baragwanath Acad Hosp, Johannesburg, South Africa
[3] Univ Witwatersrand, Johannesburg, South Africa
[4] Natl Hlth Lab Serv, Johannesburg, South Africa
[5] Univ Cape Town, Cape Town, South Africa
[6] St Georges Univ London, London, England
[7] Univ Exeter, Exeter, Devon, England
[8] Natl Inst Communicable Dis, Ctr Healthcare Associated Infect, Natl Hlth Lab Serv, Antimicrobial Resistance & Mycoses, 1 Modderfontein Rd, ZA-2131 Johannesburg, South Africa
关键词
D O I
10.3201/eid2909.230393
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
One third of patients were colonized by Candida auris during a point-prevalence survey in a neonatal unit during an outbreak in South Africa. The sensitivity of a direct PCR for rapid colonization detection was 44% compared with culture. The infection incidence rate decreased by 85% after the survey and implementation of isolation/cohorting.
引用
收藏
页码:1913 / 1916
页数:4
相关论文
共 11 条
  • [1] A high-throughput and rapid method for accurate identification of emerging multidrug-resistant Candida auris
    Ahmad, Ausaf
    Spencer, Jonathan E.
    Lockhart, Shawn R.
    Singleton, Sabrina
    Petway, David J.
    Bagarozzi, Dennis A., Jr.
    Herzegh, Owen T.
    [J]. MYCOSES, 2019, 62 (06) : 513 - 518
  • [2] Centers for Disease Control and Prevention, Screening for Candida auris Colonization
  • [3] A Candida auris Outbreak and Its Control in an Intensive Care Setting
    Eyre, David W.
    Sheppard, Anna E.
    Madder, Hilary
    Moir, Ian
    Moroney, Ruth
    Quan, T. Phuong
    Griffiths, David
    George, Sophie
    Butcher, Lisa
    Morgan, Marcus
    Newnham, Robert
    Sunderland, Mary
    Clarke, Tiphanie
    Foster, Dona
    Hoffman, Peter
    Borman, Andrew M.
    Johnson, Elizabeth M.
    Moore, Ginny
    Brown, Colin S.
    Walker, A. Sarah
    Peto, Tim E. A.
    Crook, Derrick W.
    Jeffery, Katie J. M.
    [J]. NEW ENGLAND JOURNAL OF MEDICINE, 2018, 379 (14) : 1322 - 1331
  • [4] A Novel Transdermal Application for Clearing Skin Colonization by Candida auris
    Ghannoum, M.
    Herrada, J.
    McCormick, T. S.
    Long, L.
    [J]. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2021, 65 (05)
  • [5] Murine model of colonization with fungal pathogen Candida auris to explore skin tropism, host risk factors and therapeutic strategies
    Huang, Xin
    Hurabielle, Charlotte
    Drummond, Rebecca A.
    Bouladoux, Nicolas
    Desai, Jigar, V
    Sim, Choon K.
    Belkaid, Yasmine
    Lionakis, Michail S.
    Segre, Julia A.
    [J]. CELL HOST & MICROBE, 2021, 29 (02) : 210 - +
  • [6] Moema I, 2017, FEAD FIELD EPIDEMIOL
  • [7] Integrated genomic, epidemiologic investigation of Candida auris skin colonization in a skilled nursing facility
    Proctor, Diana M.
    Dangana, Thelma
    Sexton, D. Joseph
    Fukuda, Christine
    Yelin, Rachel D.
    Stanley, Mary
    Bell, Pamela B.
    Baskaran, Sangeetha
    Deming, Clay
    Chen, Qiong
    Conlan, Sean
    Park, Morgan
    Welsh, Rory M.
    Vallabhaneni, Snigdha
    Chiller, Tom
    Forsberg, Kaitlin
    Black, Stephanie R.
    Pacilli, Massimo
    Kong, Heidi H.
    Lin, Michael Y.
    Schoeny, Michael E.
    Litvintseva, Anastasia P.
    Segre, Julia A.
    Hayden, Mary K.
    [J]. NATURE MEDICINE, 2021, 27 (08) : 1401 - +
  • [8] An outbreak due to Candida auris with prolonged colonisation and candidaemia in a tertiary care European hospital
    Ruiz-Gaitan, Alba
    Moret, Ana M.
    Tasias-Pitarch, Maria
    Aleixandre-Lopez, Ana I.
    Martinez-Morel, Hector
    Calabuig, Eva
    Salavert-Lleti, Miguel
    Ramirez, Paula
    Lopez-Hontangas, Jose L.
    Hagen, Ferry
    Meis, Jacques F.
    Mollar-Maseres, Juan
    Peman, Javier
    [J]. MYCOSES, 2018, 61 (07) : 498 - 505
  • [9] Positive Correlation Between Candida auris Skin-Colonization Burden and Environmental Contamination at a Ventilator-Capable Skilled Nursing Facility in Chicago
    Sexton, D. Joseph
    Bentz, Meghan L.
    Welsh, Rory M.
    Derado, Gordana
    Furin, William
    Rose, Laura J.
    Noble-Wang, Judith
    Pacilli, Massimo
    McPherson, Tristan D.
    Black, Stephanie
    Kemble, Sarah K.
    Herzegh, Owen
    Ahmad, Ausaf
    Forsberg, Kaitlin
    Jackson, Brendan
    Litvintseva, Anastasia P.
    [J]. CLINICAL INFECTIOUS DISEASES, 2021, 73 (07) : 1142 - 1148
  • [10] Sexton DJ, 2018, J CLIN MICROBIOL, V56, DOI [10.1128/jcm.01337-18, 10.1128/JCM.01337-18]