Current status and prospect of treatments for recurrent hepatocellular carcinoma

被引：13

作者：

Yang, Yu-Qing ^{[1
]}

Wen, Zhen-Yu ^{[2
]}

Liu, Xiao-Yan ^{[3
]}

Ma, Zhen-Hu ^{[4
]}

Liu, Yan-E ^{[1
]}

Cao, Xue-Ying ^{[4
]}

Hou, Li ^{[4
]}

Xie, Hui ^{[4
,5
]}

机构：

[1] Jilin Univ, Dept Epidemiol & Biostat, Changchun 130021, Jilin, Peoples R China

[2] Jilin Univ, Dept Occupat & Environm Hlth, Changchun 130021, Jilin, Peoples R China

[3] Fifth Med Ctr Chinese PLA Gen Hosp, Sr Dept Hepatol, Beijing 100039, Peoples R China

[4] Fifth Med Ctr Chinese PLA Gen Hosp, Senior Dept Oncol, Beijing 100039, Peoples R China

[5] Fifth Med Ctr Chinese PLA Gen Hosp, Dept Oncol, 100 Western 4th Ring Middle Rd, Beijing 100039, Peoples R China

来源：

WORLD JOURNAL OF HEPATOLOGY | 2023年 / 15卷 / 02期

关键词：

Review; Recurrence; Hepatocellular carcinoma; Hepatectomy; Liver transplantation; Transcatheter arterial chemoembolization; TRANSCATHETER ARTERIAL CHEMOEMBOLIZATION; SALVAGE LIVER-TRANSPLANTATION; C-REACTIVE PROTEIN; HEPATITIS-B-VIRUS; ADJUVANT INTERFERON THERAPY; BODY RADIATION-THERAPY; INTENSIVE FOLLOW-UP; RADIOFREQUENCY ABLATION; TRANSARTERIAL CHEMOEMBOLIZATION; INTRAHEPATIC RECURRENCE;

D O I：

10.4254/wjh.v15.i2.129

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

Owing to its heterogeneous and highly aggressive nature, hepatocellular carcinoma (HCC) has a high recurrence rate, which is a non-negligible problem despite the increasing number of available treatment options. Recent clinical trials have attempted to reduce the recurrence and develop innovative treatment options for patients with recurrent HCC. In the event of liver remnant recurrence, the currently available treatment options include repeat hepatectomy, salvage liver transplantation, tumor ablation, transcatheter arterial chemoembolization, stereotactic body radiotherapy, systemic therapies, and combination therapy. In this review, we summarize the strategies to reduce the recurrence of high-risk tumors and aggressive therapies for recurrent HCC. Additionally, we discuss methods to prevent HCC recurrence and prognostic models constructed based on predictors of recurrence to develop an appropriate surveillance program.

引用

页码：129 / 150

页数：22