Trust in Medical Research: A Comparative Study among Patients at a Regional Referral Hospital and Community Members in Lira District, Northern Uganda

被引:1
作者
Pulle, Jafesi [1 ,2 ,5 ]
Loue, Sana [3 ]
Kiwanuka, Gertrude N. [4 ]
Francis, Bajunirwe [1 ]
机构
[1] Mbarara Univ Sci & Technol, Dept Community Hlth, Mbarara, Uganda
[2] Uganda Heart Inst, Rheumat Heart Dis Res Collaborat, Kampala, Uganda
[3] Case Western Reserve Univ, Sch Med, Dept Bioeth, Cleveland, OH USA
[4] Mbarara Univ Sci & Technol, Dept Biochem, Mbarara, Uganda
[5] POB 1410, Mbarara, Uganda
基金
美国国家卫生研究院;
关键词
Trust; medical research; research ethics; CBPR; & RCR; RESEARCH PARTICIPATION; RACIAL-DIFFERENCES; CLINICAL-TRIALS; WILLINGNESS;
D O I
10.1177/15562646231224374
中图分类号
B82 [伦理学(道德学)];
学科分类号
摘要
Events such as the Tuskegee syphilis study shaped how the public perceives and trusts medical research globally. However, few studies have examined trust in medical research in developing countries. We tested the hypothesis that levels of trust may be lower among community members compared to hospitalized persons in Uganda. We enrolled 296 participants in rural northern Uganda, and 148(50%) were from the community, 192(65%) were female. Mean level of trust for medical research was higher among hospitalized persons compared to community members (p = 0.0001). Previous research participation (p = 0.03), and willingness to participate in future research (p = 0.001) were positively associated with trust. Medical personnel should engage more with the communities in which they practice fostering trust in medical research.
引用
收藏
页码:48 / 57
页数:10
相关论文
共 29 条
[1]   TUSKEGEE AND THE HEALTH OF BLACK MEN [J].
Alsan, Marcella ;
Wanamaker, Marianne .
QUARTERLY JOURNAL OF ECONOMICS, 2018, 133 (01) :407-455
[2]  
[Anonymous], 2010, MANUAL RES ETHICS CO, P126, DOI DOI 10.1017/CBO9780511550089.028
[3]   Shared-decision-making Behavior in Hospitalized Patients: Investigating the Impact of Patient's Trust in Physicians, Emotional Support, Informational Support, and Tendency to Excuse Using a Structural Equation Modeling Approach [J].
Chegini, Zahra ;
Islam, Sheikh Mohammed Shariful .
JOURNAL OF PATIENT EXPERIENCE, 2021, 8
[4]   Factors associated with willingness to participate in clinical trials: a nationwide survey study [J].
Chu, Sang Hui ;
Kim, Eun Jung ;
Jeong, Seok Hee ;
Park, Geu Lee .
BMC PUBLIC HEALTH, 2015, 15
[5]  
Diaz VA, 2008, FAM MED, V40, P46
[6]  
Dictionary Cambridge., 2008, Cambridge Advance Learner's Dictionary, V3rd
[7]   The Anatomy of Research Scandals [J].
Elliott, Carl .
HASTINGS CENTER REPORT, 2017, 47 (03) :insidebackcover
[8]   Factors Influencing the Research Participation of Adults with Autism Spectrum Disorders [J].
Haas, Kaaren ;
Costley, Debra ;
Falkmer, Marita ;
Richdale, Amanda ;
Sofronoff, Kate ;
Falkmer, Torbjoern .
JOURNAL OF AUTISM AND DEVELOPMENTAL DISORDERS, 2016, 46 (05) :1793-1805
[9]  
Hall Mark A, 2006, J Health Organ Manag, V20, P456, DOI 10.1108/14777260610701812
[10]   Measuring trust in medical researchers [J].
Hall, Mark A. ;
Camacho, Fabian ;
Lawlor, Janice S. ;
DePuy, Venita ;
Sugarman, Jeremy ;
Weinfurt, Kevin .
MEDICAL CARE, 2006, 44 (11) :1048-1053