Commentary on "Brain Injury During Transition in the Newborn With Congenital Heart Disease: Hazards of the Preoperative Period"

被引:0
作者
Lynch, Jennifer M. [1 ,4 ]
Gaynor, J. William [2 ]
Licht, Daniel J. [3 ]
机构
[1] Childrens Hosp Philadelphia, Div Cardiothorac Anesthesiol, Philadelphia, PA USA
[2] Childrens Hosp Philadelphia, Div Cardiothorac Surg, Philadelphia, PA USA
[3] Perinatal Pediat Inst, Childrens Natl, Washington, DC USA
[4] Childrens Hosp Philadelphia, Div Cardiothorac Anesthesiol, 3401 Civ Ctr Blvd, Philadelphia, PA 19104 USA
关键词
GREAT-ARTERIES; TRANSPOSITION; SURGERY; OUTCOMES; INFANTS; COSTS; TIME;
D O I
10.1016/j.spen.2023.101075
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Infants born with critical congenital heart disease are at risk for neurodevelopmental morbidities later in life. In-utero differences in fetal circulation lead to vulnerabilities which lead to an increased incidence of stroke, white matter injury, and brain immaturity. Recent work has shown these infants may be most vulnerable to brain injury during the early neonatal period when they are awaiting their cardiac surgeries. Novel imaging and monitoring modalities are being employed to investigate this crucial time period and elucidate the precise timing and cause of brain injury in this population. Semin Pediatr Neurol 47:101075 (c) 2023 Elsevier Inc. All rights reserved.
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页数:2
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