Hypoparathyroidism and Fahr's Syndrome: A Case Series

被引:3
作者
Berrabeh, Soumiya [1 ,2 ]
Messaoudi, Najoua [1 ,2 ]
Elmehraoui, Ouafae [1 ,2 ]
Assarrar, Imane [1 ,2 ]
Karabila, Ikram [1 ,2 ]
Jamal, Anouar [1 ,2 ]
Zeryouh, Nabila [1 ,2 ]
Rouf, Siham [1 ,3 ]
Latrech, Hanane [1 ,3 ]
机构
[1] Mohammed VI Univ Hosp Ctr, Dept Endocrinol Diabetol & Nutr, Oujda, Morocco
[2] Mohamed First Univ, Fac Med & Pharm, Dept Endocrinol Diabetol & Nutr, Oujda, Morocco
[3] Mohamed First Univ, Fac Med & Pharm, Dept Endocrinol Diabetol & Nutr, Lab Epidemiol Clin Res & Publ Hlth, Oujda, Morocco
关键词
fahr's disease; neurological disorders; phosphocalcic metabolism; dysparathyroidism; intracerebral; calcifications; basal ganglia; CEREBRAL CALCIFICATIONS; BASAL GANGLIA; DISEASE; BRAIN;
D O I
10.7759/cureus.40502
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Fahr's syndrome is defined by the presence of striato-pallido-dentate calcifications. It is a rare entity with clinical polymorphism, and it occurs in patients with dysparathyroidism, especially those with hypoparathyroidism. It must be distinguished from Fahr's disease (FD), which is defined by the presence of intracerebral calcifications without phosphocalcic metabolism abnormality. In this paper, we report the particulars of five patients diagnosed with Fahr's syndrome revealed by neurological and cognitive disorders, seizures, and abnormal movements associated with tetany crisis. In all cases, brain imaging and biological examinations led to the diagnosis of Fahr's syndrome related to hypoparathyroidism. The evolution was favorable after treatment. Fahr's syndrome is a rare and serious condition for which treatment is simple and effective. Our observations shed light on the necessity of evaluating phosphocalcic metabolism and exploring cerebral calcifications in patients with neurological disorders.
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页数:7
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