Pharmacotherapy for Treatment-Resistant Depression Antidepressants and Atypical Antipsychotics

被引：14
作者：
Vas, Collin [1 ]
Jain, Ayush [2 ]
Trivedi, Mili [3 ]
Jha, Manish Kumar [4 ]
Mathew, Sanjay J. [5 ]
机构：
[1] UT Southwestern Med Ctr, Dallas, TX USA
[2] Shri Ram Sch, Gurgaon, Haryana, India
[3] Colleyville Heritage High Sch, Colleyville, TX USA
[4] UT Southwestern Med Ctr, Ctr Depress Res & Clin Care, 5323 Harry Hines Blvd, Dallas, TX 75390 USA
[5] Baylor Coll Med, Michael E DeBakey VA Med Ctr, Menninger Dept Psychiat & Behav Sci, Menninger Clin, Houston, TX USA
来源：
PSYCHIATRIC CLINICS OF NORTH AMERICA | 2023年 / 46卷 / 02期
关键词：
Major depressive disorder; Antidepressants; Treatment-resistant depression; Atypical antipsychotics; Aripiprazole; Brexpiprazole; Cariprazine; Quetiapine; EXTENDED-RELEASE QUETIAPINE; STAR-ASTERISK-D; DOUBLE-BLIND; INADEQUATE-RESPONSE; OLANZAPINE/FLUOXETINE COMBINATION; ADJUNCTIVE THERAPY; ARIPIPRAZOLE AUGMENTATION; OUTPATIENTS FINDINGS; DISORDER; EFFICACY;
D O I：
10.1016/j.psc.2023.02.012
中图分类号：
R749 [精神病学];
学科分类号：
100205 ;
摘要：
Major depressive disorder (MDD) is an often chronic and/or recurrent disorder that is associated with dysfunctions in multiple aspects of life including work and non-work related productivity, psychosocial function, and quality of life.1-5It is widely prevalent and is estimated to affect one in five adults in the United States during their lifetime.6 Although universal screening and use of measurement-based care can assist with
引用
收藏
页码：261 / 275
页数：15
相关论文
共 80 条
[31]   A Randomized, Placebo-Controlled Study of the Efficacy and Safety of Fixed-Dose Brexpiprazole 2 mg/d as Adjunctive Treatment of Adults With Major Depressive Disorder [J].
Hobart, Mary ;
Skuban, Aleksandar ;
Zhang, Peter ;
Augustine, Carole ;
Brewer, Claudette ;
Hefting, Nanco ;
Sanchez, Raymond ;
McQuade, Robert D. .
JOURNAL OF CLINICAL PSYCHIATRY, 2018, 79 (04)
[32]   Efficacy and safety of flexibly dosed brexpiprazole for the adjunctive treatment of major depressive disorder: a randomized, active-referenced, placebo-controlled study [J].
Hobart, Mary ;
Skuban, Aleksandar ;
Zhang, Peter ;
Josiassen, Mette Krog ;
Hefting, Nanco ;
Augustine, Carole ;
Brewer, Claudette ;
Sanchez, Raymond ;
McQuade, Robert D. .
CURRENT MEDICAL RESEARCH AND OPINION, 2018, 34 (04) :633-642
[33]   Treatment Patterns During Major Depressive Episodes Among Patients with Major Depressive Disorder: A Retrospective Database Analysis [J].
Jain, Rakesh ;
Higa, Sara ;
Keyloun, Katelyn ;
Park, Julie ;
Bonafede, Machaon ;
Tung, Amy ;
Gillard, Patrick ;
Cutler, Andrew J. .
DRUGS-REAL WORLD OUTCOMES, 2022, 9 (03) :477-486
[34]   N-Desalkylquetiapine, a potent norepinephrine reuptake inhibitor and partial 5-HT1A agonist, as a putative mediator of quetiapine's antidepressant activity [J].
Jensen, Niels H. ;
Rodriguiz, Ramona M. ;
Caron, Marc G. ;
Wetsel, William C. ;
Rothman, Richard B. ;
Roth, Bryan L. .
NEUROPSYCHOPHARMACOLOGY, 2008, 33 (10) :2303-2312
[35]  
Jha M.K., 2021, J CLIN PSYCHIAT, V82
[36]   Association between irritability and suicidal ideation in three clinical trials of adults with major depressive disorder [J].
Jha, Manish K. ;
Minhajuddin, Abu ;
Chin Fatt, Cherise ;
Kircanski, Katharina ;
Stringaris, Argyris ;
Leibenluft, Ellen ;
Trivedi, Madhukar H. .
NEUROPSYCHOPHARMACOLOGY, 2020, 45 (13) :2147-2154
[37]   A Structured Approach to Detecting and Treating Depression in Primary Care: VitalSign6 Project [J].
Jha, Manish K. ;
Grannemann, Bruce D. ;
Trombello, Joseph M. ;
Clark, E. Will ;
Eidelman, Sara Levinson ;
Lawson, Tiffany ;
Greer, Tracy L. ;
Rush, A. John ;
Trivedi, Madhukar H. .
ANNALS OF FAMILY MEDICINE, 2019, 17 (04) :326-335
[38]   Screening and Management of Depression in Patients With Cardiovascular Disease JACC State-of-the-Art Review [J].
Jha, Manish K. ;
Qamar, Arman ;
Vaduganathan, Muthiah ;
Charney, Dennis S. ;
Murrough, James W. .
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2019, 73 (14) :1827-1845
[39]   Irritability and Its Clinical Utility in Major Depressive Disorder: Prediction of Individual-Level Acute-Phase Outcomes Using Early Changes in Irritability and Depression Severity [J].
Jha, Manish K. ;
Minhajuddin, Abu ;
South, Charles ;
Rush, A. John ;
Trivedi, Madhukar H. .
AMERICAN JOURNAL OF PSYCHIATRY, 2019, 176 (05) :358-366
[40]  
Jha Manish K, 2018, Focus (Am Psychiatr Publ), V16, P279, DOI [10.1176/appi.focus.20180013, 10.1176/appi.focus.20180013]
12345678