MicroRNA biosensors in lung cancer

被引：16

作者：

Shaterabadi, Donya ^{[1
]}

Sani, Maryam Zamani ^{[2
]}

Rahdan, Fereshteh ^{[3
]}

Taghizadeh, Mohammad ^{[4
]}

Rafiee, Maedeh ^{[5
]}

Dorosti, Nafiseh ^{[6
]}

Dianatinasab, Aria ^{[7
]}

Taheri-Anganeh, Mortaza ^{[8
]}

Asadi, Peyman ^{[9
]}

Khatami, Seyyed Hossein ^{[10
,12
]}

Movahedpour, Ahmad ^{[11
]}

机构：

[1] Tabriz Univ Med Sci, Fac Adv Med Sci, Dept Med Nanotechnol, Tabriz, Iran

[2] Tabriz Univ Med Sci, Fac Med, Dept Biochem & Clin Labs, Tabriz, Iran

[3] Tabriz Univ Med Sci, Fac Adv Med Sci, Dept Med Biotechnol, Tabriz, Iran

[4] Tabriz Univ Med Sci, Fac Adv Med Sci, Dept Mol Med, Tabriz, Iran

[5] Univ Wyoming, Dept Vet Sci, 1174 Snowy Range Rd, Laramie, WY 82070 USA

[6] Shahid Beheshti Univ Med Sci, Sch Adv Technol Med, Dept Med Nanotechnol, Tehran, Iran

[7] Shiraz Univ Med Sci, Sch Med, Dept Biochem, Shiraz, Iran

[8] Urmia Univ Med Sci, Cellular & Mol Med Res Inst, Cellular & Mol Res Ctr, Orumiyeh, Iran

[9] Mazandaran Univ Med Sci, Fac Adv Technol Med, Dept Med Nanotechnol, Sari, Iran

[10] Shahid Beheshti Univ Med Sci, Sch Med, Dept Clin Biochem, Tehran, Iran

[11] Behbahan Fac Med Sci, Behbahan, Iran

[12] Shahid Beheshti Univ Med Sci, Sch Med, Dept Clin Biochem, Clin Biochem, Tehran, Iran

来源：

CLINICA CHIMICA ACTA | 2024年 / 552卷

关键词：

microRNA; Electrochemical Biosensors; Nanobiosensor; Lung Cancers; GRAPHENE OXIDE; DIAGNOSIS; IMMUNOSENSOR; INHIBITION;

D O I：

10.1016/j.cca.2023.117676

中图分类号：

R446 [实验室诊断]; R-33 [实验医学、医学实验];

学科分类号：

1001 ;

摘要：

Lung cancer has been one of the leading causes of death over the past century. Unfortunately, the reliance on conventional methods to diagnose the phenotypic properties of tumors hinders early-stage cancer diagnosis. However, recent advancements in identifying disease-specific nucleotide biomarkers, particularly microRNAs, have brought us closer to early-stage detection. The roles of miR-155, miR-197, and miR-182 have been established in stage I lung cancer. Recent progress in synthesizing nanomaterials with higher conductivity has enhanced the diagnostic sensitivity of electrochemical biosensors, which can detect low concentrations of targeted biomarkers. Therefore, this review article focuses on exploring electrochemical biosensors based on microRNA in lung cancer.

引用

页数：9

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