Management of neuropsychiatric adverse events in a prostate cancer patient undergoing chimeric antigen receptor T-cell immunotherapy (a phase I clinical trial): A case report

被引：0

作者：

Tang, Ruijin ^{[1
]}

Wang, Qiong ^{[2
]}

Han, Jing ^{[1
]}

Shi, Ming ^{[3
]}

机构：

[1] Xuzhou Med Univ, Sch Nursing, Xuzhou, Peoples R China

[2] Xuzhou Med Univ, Dept Urol, Affiliated Hosp, Xuzhou, Peoples R China

[3] Xuzhou Med Univ, Natl & Local Joint Engn Lab Tumor Biotherapy, Clin Coll 1, Xuzhou, Peoples R China

来源：

ASIA-PACIFIC JOURNAL OF ONCOLOGY NURSING | 2023年 / 10卷 / 04期

基金：

中国国家自然科学基金;

关键词：

CAR T -cell immunotherapy; Side effects; Anxiety; Psychological support; Cancer care; VISUAL ANALOG SCALE; THERAPY;

D O I：

10.1016/j.apjon.2023.100211

中图分类号：

R47 [护理学];

学科分类号：

1011 ;

摘要：

In previous clinical trials, chimeric antigen receptor T-cell immunotherapy has shown preliminary efficacy in patients with malignant solid tumors. However, the occurrence of adverse events, particularly neuropsychiatric adverse events (eg, anxiety) and cognitive dysfunction, during the course of treatment may reduce patient compliance and pose a threat to their safety. Nurses are in a unique position to promptly identify and manage such complications, thereby facilitating early diagnosis and treatment, as well as improving clinical and patient outcomes. Moreover, nurses can promote compliance through the provision of psychological support to patients.

引用

页数：5

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