High-intensity focused ultrasound for the treatment of fibroids: A single-center experience in Singapore

被引:7
作者
Jindal, Smita [1 ]
Jung, Jacqueline [1 ,2 ]
Lee, KeenWhye
Chern, Bernard [1 ]
机构
[1] KK Womens & Childrens Hosp, Dept Minimally Invas Surg, Singapore, Singapore
[2] Gleneagles Hosp, Singapore, Singapore
来源
GYNECOLOGY AND MINIMALLY INVASIVE THERAPY-GMIT | 2023年 / 12卷 / 01期
关键词
High-intensity focused ultrasound; noninvasive; ultrasound; ultrasound-guided high-intensity focused ultrasound; uterine fibroid; UTERINE ARTERY EMBOLIZATION; LAPAROSCOPIC MYOMECTOMY; ABDOMINAL MYOMECTOMY; RECURRENCE; SURGERY; ADENOMYOSIS; ABLATION; SAFETY; MYOMA; PREDICTORS;
D O I
10.4103/gmit.gmit_102_22
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
Objectives: Uterine fibroids and adenomyosis are common gynecological conditions that often require surgical treatment. Minimally invasive interventions such as ultrasound-guided high-intensity focused ultrasound (USgHIFU) are gaining popularity as they avoid surgical morbidity and conserve the uterus. We present a single-center experience on the use of USgHIFU for the treatment of fibroids and adenomyosis. Materials and Methods: This was a retrospective study of 167 patients who underwent USgHIFU for uterine fibroids and adenomyosis between July 2018 and December 2020. Relevant demographic data and pre- and post-intervention fibroid volume, symptom severity scores (SSS), and health-related quality of life (QOL) scores were collected and compared. The paired t-test or Wilcoxon signed-rank test was used to compare the difference before and after treatment. P < 0.001 was considered statistically significant. Results: One hundred and sixty-seven patients with fibroids or adenomyosis were included in this study. The mean age of the cohort was 42-year-old. USgHIFU treatment led to a reduction in mean fibroid volume, improvement in SSS, and health-related QOL scores. The average reduction in mean fibroid volume was 68% and 75% at 6 and 12 months, respectively. There was a significant reduction in SSS (46.9 [pre] vs. 15.6 [post], P < 0.001) and improvement in health-related QOL scores at 6 months (58 [pre] vs. 86 [post], P < 0.001). The re-intervention rate following USgHIFU was 7.7% and successful pregnancy post USgHIFU was reported in 6 patients.Conclusion: USgHIFU is safe and effective. In women who desire fertility or are not suitable for surgery, it is a good alternative option. It should be included in the armamentarium for the treatment of uterine fibroids and adenomyosis.
引用
收藏
页码:15 / 25
页数:11
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